Retinal detachment induces massive immediate reorganization in visual cortex

Leisa M. Schmid, Marcello G.P. Rosa, Michael B. Calford

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43 Citations (Scopus)

Abstract

Large inactive regions of the retina of adult cats were produced by the novel method of inducing monocular retinal detachment. Within a few hours, neurones throughout the detachment projection zone in primary visual cortex (55-136 mm2), including some > 4.5 mm from its boundary, were found to have large receptive fields displaced onto intact retina. The new receptive fields of some neurones represented shifts of up to 9 mm across the retinotopic representation. For these rapid changes to occur pre-existing viable circuits must provide a cortical locus with inputs from a wide extent of the retina. Receptive fields, and the retinotopic map, for stimulation of the other eye were unchanged.

Original languageEnglish
Pages (from-to)1349-1353
Number of pages5
JournalNeuroReport
Volume6
Issue number9
DOIs
Publication statusPublished - 1 Jan 1995
Externally publishedYes

Keywords

  • Cats
  • Reorganization
  • Retinal detachment
  • Visual cortex

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