TY - JOUR
T1 - Research prioritization of interventions for the primary prevention of preterm birth
T2 - An international survey
AU - Allotey, John
AU - Matei, Anca
AU - Husain, Shahid
AU - Newton, Sian
AU - Dodds, Julie
AU - Armson, Anthony B.
AU - Khan, Khalid S.
AU - Vogel, Joshua P.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Objective: To identify research priorities of interventions for the primary prevention of preterm birth (PTB), by conducting an international stakeholder survey. Study design: A prospective cross-sectional online survey was conducted in November 2016. Fifteen interventions to prevent spontaneous PTB were identified and ranked by stakeholders (n = 159) in the field of maternal and perinatal health research, using nine equally weighted criteria. Medians and interquartile ranges (IQRs) were calculated and the interventions ranked accordingly. Results: Respondents to the survey were from 46 different countries, mostly from low and middle-income countries (62%, 99/159) and were mainly clinicians (80%, 127/159). Of the fifteen interventions ranked, the following five were identified as research priorities in the primary prevention of PTB: dietary counselling and nutritional education, risk scoring, vitamin D supplementation, exercise and antioxidant supplementation. Conclusion: We have identified research priorities of interventions to prevent spontaneous PTB through a global stakeholder survey. The interventions prioritized in this exercise can be used by researchers, grant funding bodies and research-policy decision makers to inform calls on future clinical trials or individual patient data meta-analyses on the primary prevention of PTB.
AB - Objective: To identify research priorities of interventions for the primary prevention of preterm birth (PTB), by conducting an international stakeholder survey. Study design: A prospective cross-sectional online survey was conducted in November 2016. Fifteen interventions to prevent spontaneous PTB were identified and ranked by stakeholders (n = 159) in the field of maternal and perinatal health research, using nine equally weighted criteria. Medians and interquartile ranges (IQRs) were calculated and the interventions ranked accordingly. Results: Respondents to the survey were from 46 different countries, mostly from low and middle-income countries (62%, 99/159) and were mainly clinicians (80%, 127/159). Of the fifteen interventions ranked, the following five were identified as research priorities in the primary prevention of PTB: dietary counselling and nutritional education, risk scoring, vitamin D supplementation, exercise and antioxidant supplementation. Conclusion: We have identified research priorities of interventions to prevent spontaneous PTB through a global stakeholder survey. The interventions prioritized in this exercise can be used by researchers, grant funding bodies and research-policy decision makers to inform calls on future clinical trials or individual patient data meta-analyses on the primary prevention of PTB.
KW - Intervention
KW - Preterm birth
KW - Primary prevention
KW - Research priorities
KW - Survey
UR - http://www.scopus.com/inward/record.url?scp=85060670586&partnerID=8YFLogxK
U2 - 10.1016/j.ejogrb.2019.01.021
DO - 10.1016/j.ejogrb.2019.01.021
M3 - Article
C2 - 30711217
AN - SCOPUS:85060670586
SN - 0301-2115
VL - 236
SP - 240
EP - 248
JO - European Journal of Obstetrics & Gynecology and Reproductive Biology
JF - European Journal of Obstetrics & Gynecology and Reproductive Biology
ER -