adult respiratory failure.5 Although use of cardiac ECLS was already growing, its use increased dramatically in some countries
after the publication of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial.2,6 The current growth of ECLS is outpacing the evidence base supporting its use.7-9 For example, in the last decade, only one large randomized clinical trial assessing the efficacy of ECLS for respiratory failure has been published; none has been published for cardiac failure.
This lack of data leaves us without definitive answers to a number of important questions, including the most fundamental: When is
ECLS indicated? Also, is it superior to the best current standard of care?
- extracorporeal life support
- research networks