Reproduction Reborn: How Science, Ethics, and Law Shape Mitochondrial Replacement Therapies

Diana M. Bowman (Editor), Walter G. Johnson (Editor), Karinne Ludlow (Editor)

Research output: Book/ReportEdited Bookpeer-review

1 Citation (Scopus)

Abstract

Mitochondrial replacement therapies (MRT) represent the most recent advancement in assisted reproductive technologies, allowing some women with mitochondrial diseases to birth for the first time-babies without those diseases. MRT, however, are not without controversy: DNA is intentionally changed, and resulting babies have DNA from three people. Additionally, the change to DNA is considered germline therapy in some countries and is therefore banned. With MRT prohibited in some countries but commercially available in multiple other jurisdictions, policymakers and other key stakeholders are faced with questions about the legal and ethical challenges surrounding MRT and the rights and responsibilities of parents and donor mothers, MRT's use to address broader problems of infertility, and issues surrounding the notions of family. This edited volume draws together leading experts from across the world and various disciplines to explore the novel legal, ethical, and policy questions posed by MRT, along with the broader societal and governance implications.

Original languageEnglish
Place of PublicationOxford UK
PublisherOxford University Press
Number of pages283
Edition1st
ISBN (Electronic)9780197616239
ISBN (Print)9780197616208, 9780197616192
DOIs
Publication statusPublished - 2023

Keywords

  • assisted reproductive technologies
  • ethics
  • governance
  • infertility
  • law
  • medical tourism
  • mitochondrial replacement therapies
  • regulation
  • science
  • therapeutic
  • Introduction

    Bowman, D. M., Johnson, W. G. & Ludlow, K., 2023, Reproduction Reborn: How Science, Ethics, and Law Shape Mitochondrial Replacement Therapies. Bowman, D. M., Johnson, W. G. & Ludlow, K. (eds.). 1st ed. Oxford UK: Oxford University Press, p. 1-13 13 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

  • Mitochondrial replacement techniques: a critical review of the ethical issues

    Sparrow, R., Koplin, J. & Mills, C., 2023, Reproduction Reborn: How Science, Ethics, and Law Shape Mitochondrial Replacement Therapies. Bowman, D., Ludlow, K. & Johnson, W. G. (eds.). 1st ed. Oxford UK: Oxford University Press, p. 32-61 30 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

  • MRT in Australia

    Ludlow, K., 2023, Reproduction Reborn: How Science, Ethics, and Law Shape Mitochondrial Replacement Therapies. Bowman, D. M., Johnson, W. G. & Ludlow, K. (eds.). 1st ed. Oxford UK: Oxford University Press, p. 108-128 21 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Cite this