@article{a83985a1c754416f9cc61631568c5c87,
title = "Representativeness of the PDOPPS cohort compared to the Australian PD population",
abstract = "Background: The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) is an international, prospective study following persons treated by peritoneal dialysis (PD) to identify modifiable practices associated with improvements in PD technique and person survival. The aim of this study was to assess the representativeness of the Australian cohort included in PDOPPS compared to the complete Australian PD population, as reported to the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Methods: Adults with at least one PD treatment reported to ANZDATA Registry during the census period of PDOPPS Phase I (November 2014 to April 2018) were compared to the Australian PDOPPS cohort. The primary outcomes were the representativeness of centres and persons. Secondary outcomes explored the association of person characteristics with consent to study participation. Results: After data linkage, 511 PDOPPS participants were compared to 5616 Australians treated with PD. Within centres eligible for PDOPPS, selected centres were similar to other Australian centres. The PDOPPS participants{\textquoteright} cohort tended to include older persons, more males, a higher proportion of Caucasians and more persons with higher socioeconomic advantage compared to the Australian PD population. Differences in distribution across sex and ethnicities between the PDOPPS cohort and the overall PD population were in part due to the selection and consent processes, during which females and non-Caucasians were more likely to not consent to PDOPPS participation. Conclusion: Sampling methods used in PDOPPS allowed for good national representativeness of the included centres. However, representativeness of the unweighted PDOPPS sample was suboptimal in regard to some participant characteristics.",
keywords = "Data linkage, patient selection, peritoneal dialysis, practice patterns, registries, research design",
author = "Isabelle Ethier and Neil Boudville and Stephen McDonald and Fiona Brown and Kerr, {Peter G.} and Rowan Walker and Holt, {Stephen Geoffroy} and Badve, {Sunil V.} and Yeoungjee Cho and Carmel Hawley and Laura Robison and Donna Reidlinger and Elasma Milanzi and Brian Bieber and Keith McCullough and Johnson, {David W.}",
note = "Funding Information: The authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: Data linkage was funded by a Fresenius Medical Care Clinical Research Committee research grant (2019003438). Fresenius was not involved in study design, analysis, interpretation or decision to publish. PDOPPS Australia was funded by a National Health and Medical Research Council(NHMRC) project grant (APP1178472). Global support for the ongoing DOPPS Programmes is provided without restriction on publications. See https://www.dopps.org/AboutUs/Support.aspx for more information. IE would like to acknowledge the Centre Hospitalier de l{\textquoteright}Universit{\'e} de Montr{\'e}al and the Fondation du CHUM for their support through a fellowship grant. DJ is supported by an Australian National Health and Medical Research Council (NHMRC) Practitioner Fellowship. YC is supported by an Australian NHMRC Early Career Fellowship. Funding Information: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: NB reports personal fees from Astra-Zeneca, Baxter Healthcare and grant support from Roche, Amgen and Baxter; FB has received personal fees from Baxter Healthcare, speakers honoraria from Amgen and fees for advisory board from Fresenius Medical Care, outside the submitted work; SGH reports personal fees from Astra-Zeneca, Baxter Healthcare, Otsuka and grant support from Amgen, Baxter, Sanofi, outside the submitted work; SVB has received speakers honoraria from Amgen, Pfizer and Bayer, and fees for advisory board from Bayer and AstraZeneca, outside the submitted work, all fees paid to his institution; YC reports personal fees from Baxter Healthcare, Fresenius Medical Care, and grant support from Baxter CEC grant, NHMRC and Amgen, outside the submitted work; CH reports grants from National Health and Medical Research Council (NHMRC), grants from Shire and Baxter, trial leadership fees from GlaxoSmithKline all paid to her institution outside the submitted work; DJ reports personal fees from AWAK, Astra-Zeneca, Bayer, Ono, Baxter Healthcare and Fresenius Medical Care, and grant support from Baxter Extramural Grant and Baxter CEC Grant, outside the submitted work. The other authors do not have any interest in the information contained in the manuscript to disclose. Publisher Copyright: {\textcopyright} The Author(s) 2021.",
year = "2022",
month = jul,
doi = "10.1177/08968608211056242",
language = "English",
volume = "42",
pages = "403--414",
journal = "Peritoneal Dialysis International",
issn = "0896-8608",
publisher = "SAGE Publications Ltd",
number = "4",
}