Renal sympathetic denervation in the management of treatment-resistant hypertension

Henry Krum

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Abstract

The contribution of sympathetic activation to the genesis and progression of hypertension has been well recognised for decades [1]. A step-up has been demonstrated in muscle sympathetic nerve activity from normal to high-normal blood pressure, white coat to borderline to established hypertension, with or without left ventricular hypertrophy [2]. These data are supported by other measures of sympathetic activation in man, specifically spillover of noradrenaline into plasma. A significant increase was noted in essential hypertension patients in comparison to normotensive controls [3] in a study of renal spillover. This increase was particularly prominent in younger hypertensives, aged 20-39 years
Original languageEnglish
Title of host publicationCardio-Renal Clinical Challenges
EditorsDavid Goldsmith, Adrian Covic, Jonas Spaak
Place of PublicationCham Switzerland
PublisherSpringer
Pages181-186
Number of pages6
ISBN (Print)978-3-319-09161-7
DOIs
Publication statusPublished - 2015

Cite this

Krum, H. (2015). Renal sympathetic denervation in the management of treatment-resistant hypertension. In D. Goldsmith, A. Covic, & J. Spaak (Eds.), Cardio-Renal Clinical Challenges (pp. 181-186). Cham Switzerland: Springer. https://doi.org/10.1007/978-3-319-09162-4_17
Krum, Henry. / Renal sympathetic denervation in the management of treatment-resistant hypertension. Cardio-Renal Clinical Challenges. editor / David Goldsmith ; Adrian Covic ; Jonas Spaak. Cham Switzerland : Springer, 2015. pp. 181-186
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Krum, H 2015, Renal sympathetic denervation in the management of treatment-resistant hypertension. in D Goldsmith, A Covic & J Spaak (eds), Cardio-Renal Clinical Challenges. Springer, Cham Switzerland, pp. 181-186. https://doi.org/10.1007/978-3-319-09162-4_17

Renal sympathetic denervation in the management of treatment-resistant hypertension. / Krum, Henry.

Cardio-Renal Clinical Challenges. ed. / David Goldsmith; Adrian Covic; Jonas Spaak. Cham Switzerland : Springer, 2015. p. 181-186.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

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Krum H. Renal sympathetic denervation in the management of treatment-resistant hypertension. In Goldsmith D, Covic A, Spaak J, editors, Cardio-Renal Clinical Challenges. Cham Switzerland: Springer. 2015. p. 181-186 https://doi.org/10.1007/978-3-319-09162-4_17