Renal and systemic vascular conductances in renal wrap hypertension in rabbits

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Abstract

The contribution of renal vascular conductance to the fall in total peripheral conductance during the development of renal wrap hypertension was determined in conscious rabbits. Measurements were made 28 days after renal wrap (n = 9) or sham operation (n = 8). Blood pressure was about 50 mmHg higher in the wrapped group as compared to the sham-operated group. This was due to a fall in total peripheral conductance of about 42%. Cardiac output was not significantly different between wrap and sham groups. Renal vascular conductance was 0.42 ml/min per mmHg lower in the wrap compared to the sham-operated group (P <0.001). Total peripheral conductance was 3.93 ml/min per mmHg lower in the wrap compared to the sham group (P

Original languageEnglish
Pages (from-to)719-722
Number of pages4
JournalJournal of Hypertension
Volume6
Issue number9
Publication statusPublished - 1988
Externally publishedYes

Keywords

  • Cardiac output
  • Glomerular filtration rate
  • Page hypertension
  • Renal blood flow
  • Total peripheral conductance

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