Remodelling the malignant phenotype: Impact of EMT

Nur Akmarina Binti Mohd Said, Elizabeth Williams

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)


Epithelial to mesenchymal transition (EMT) is a highly conserved programme of events essential for normal development. As it underpins cell plasticity, migration and invasion in a number of settings it is an attractive concept to apply to the malignant phenotype. Much is known about the molecular events regulating EMT in a number of model organisms, including Drosophila, sea urchin, zebrafish, xenopus and the chick. It is increasingly apparent that EMT is a highly conserved process, and that discoveries made in these systems provide excellent insights into the understanding of the role of EMT in human malignancies.
Original languageEnglish
Pages (from-to)21 - 25
Number of pages5
JournalDrug Discovery Today
Issue number1
Publication statusPublished - 2009

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