Regulation of germinal center responses, memory B cells and plasma cell formation-an update

Lynn M. Corcoran; David M. Tarlinton

doi:10.1016/j.coi.2015.12.008

Regulation of germinal center responses, memory B cells and plasma cell formation-an update

Lynn M. Corcoran, David M. Tarlinton

Research output: Contribution to journal › Review Article › Other › peer-review

63 Citations (Scopus)

Abstract

Progress in understanding humoral immunity has been accelerated by the powerful experimental approaches of genetics, genomics and imaging. Excellent reviews of these advances appeared in 2015 in celebration of the 50th anniversary of the discovery of B cell and T cell lineages in the chicken. Here we provide a contemporary model of B cell differentiation, highlighting recent publications illuminating germinal center (GC), memory B cell and antibody-secreting plasma cell biology. The important contributions of CD4T cells to antibody responses have been thoroughly reviewed elsewhere.

Original language	English
Pages (from-to)	59-67
Number of pages	9
Journal	Current Opinion in Immunology
Volume	39
DOIs	https://doi.org/10.1016/j.coi.2015.12.008
Publication status	Published - 1 Apr 2016
Externally published	Yes

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10.1016/j.coi.2015.12.008

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abstract = "Progress in understanding humoral immunity has been accelerated by the powerful experimental approaches of genetics, genomics and imaging. Excellent reviews of these advances appeared in 2015 in celebration of the 50th anniversary of the discovery of B cell and T cell lineages in the chicken. Here we provide a contemporary model of B cell differentiation, highlighting recent publications illuminating germinal center (GC), memory B cell and antibody-secreting plasma cell biology. The important contributions of CD4T cells to antibody responses have been thoroughly reviewed elsewhere.",

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Regulation of germinal center responses, memory B cells and plasma cell formation-an update

Abstract

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