Projects per year
Abstract
A new method for the regioselective and stereoselective iodoacyloxylation of alkynes has been developed. This protocol utilizes a combination of an iodobenzene dicarboxylate and iodine to functionalize a series of activated and unactivated alkynes in an entirely selective and predictable fashion. The resultant iodo-enol esters were subsequently coupled with boronic acids to afford tetrasubstituted alkene derivatives, which could be further converted to the corresponding 1,1-disubstituted acetophenone.
Original language | English |
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Pages (from-to) | 4412 - 4418 |
Number of pages | 7 |
Journal | The Journal of Organic Chemistry |
Volume | 80 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2015 |
Projects
- 1 Finished
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Interrogating diarylquinoline toxicity with targeted organic synthesis
Baell, J. & Zhang, L.
Australian Research Council (ARC), Monash University
2/01/14 → 31/12/17
Project: Research