RECURRENT NASOPHARYNGEAL CARCINOMA—TWO LONG TERM DISEASE‐FREE REMISSIONS WITH NON‐CISPLATINUM BASED COMBINATION CHEMOTHERAPY

I. E. Haines, M. A. Schwarz, R. A. Hurley, H. M.P. Rundle

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

Two cases of locally recurrent nasopharyngeal carcinoma following maximal radiotherapy are presented. Both patients had complete resolution of disease with outpatient combination chemotherapy using Vincristine, Adriamycin and Cyclophosphamide (VAC), and are disease free, and working full time, 3 and 4 years later, respectively. The significant relapse rate of nasopharyngeal carcinoma after initial radiotherapy is outlined, and the reported limitations of radiotherapy and chemotherapy in this situation are discussed. The survival curve for this disease appears to plateau at 2–3 years. This appears to be the first reported outpatient combination chemotherapy programme to produce long term disease‐free remission in recurrent disease.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalAustralian and New Zealand Journal of Surgery
Volume55
Issue number2
DOIs
Publication statusPublished - 1 Jan 1985

Keywords

  • chemotherapy
  • recurrent nasopharyngeal carcinoma

Cite this

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abstract = "Two cases of locally recurrent nasopharyngeal carcinoma following maximal radiotherapy are presented. Both patients had complete resolution of disease with outpatient combination chemotherapy using Vincristine, Adriamycin and Cyclophosphamide (VAC), and are disease free, and working full time, 3 and 4 years later, respectively. The significant relapse rate of nasopharyngeal carcinoma after initial radiotherapy is outlined, and the reported limitations of radiotherapy and chemotherapy in this situation are discussed. The survival curve for this disease appears to plateau at 2–3 years. This appears to be the first reported outpatient combination chemotherapy programme to produce long term disease‐free remission in recurrent disease.",
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RECURRENT NASOPHARYNGEAL CARCINOMA—TWO LONG TERM DISEASE‐FREE REMISSIONS WITH NON‐CISPLATINUM BASED COMBINATION CHEMOTHERAPY. / Haines, I. E.; Schwarz, M. A.; Hurley, R. A.; Rundle, H. M.P.

In: Australian and New Zealand Journal of Surgery, Vol. 55, No. 2, 01.01.1985, p. 153-156.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Haines, I. E.

AU - Schwarz, M. A.

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AU - Rundle, H. M.P.

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AB - Two cases of locally recurrent nasopharyngeal carcinoma following maximal radiotherapy are presented. Both patients had complete resolution of disease with outpatient combination chemotherapy using Vincristine, Adriamycin and Cyclophosphamide (VAC), and are disease free, and working full time, 3 and 4 years later, respectively. The significant relapse rate of nasopharyngeal carcinoma after initial radiotherapy is outlined, and the reported limitations of radiotherapy and chemotherapy in this situation are discussed. The survival curve for this disease appears to plateau at 2–3 years. This appears to be the first reported outpatient combination chemotherapy programme to produce long term disease‐free remission in recurrent disease.

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