Recurrent membranous nephropathy after transplantation: donor antigen and HLA converge in defining risk

Kate J. Robson, A. Richard Kitching

Research output: Contribution to journalComment / DebateOtherpeer-review

Abstract

Membranous nephropathy, like many forms of glomerulonephritis, is an HLA-associated autoimmune disease that can recur in the transplanted kidney. In this issue of Kidney International, Berchtold and colleagues publish an intriguing and important paper on risk factors for recurrent post-transplant membranous nephropathy due to autoimmunity to PLA2R1. They found that the genetics of both the autoantigen and donor HLA are important determinants of the risk of recurrent disease in the graft.

Original languageEnglish
Pages (from-to)545-548
Number of pages4
JournalKidney International
Volume99
Issue number3
DOIs
Publication statusPublished - Mar 2021

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