Abstract
Objective: The purpose of this study was to investigate the recurrence risk of preterm birth (<37 weeks' gestation) in a subsequent singleton pregnancy after a previous nulliparous preterm twin delivery. Study Design: We included 1957 women who delivered a twin gestation and a subsequent singleton pregnancy from the Netherlands Perinatal Registry. We compared the outcome of subsequent singleton pregnancy of women with a history of preterm delivery to the pregnancy outcome of women with a history of term twin delivery. Results: Preterm birth in the twin pregnancy occurred in 1075 women (55%) vs 882 women (45%) who delivered at term. The risk of subsequent spontaneous singleton preterm birth was significantly higher after preterm twin delivery (5.2% vs 0.8%; odds ratio, 6.9; 95% confidence interval, 3.1-15.2). Conclusion: Women who deliver a twin pregnancy are at greater risk for delivering prematurely in a subsequent singleton pregnancy.
Original language | English |
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Pages (from-to) | 279.e1-279.e7 |
Number of pages | 7 |
Journal | American Journal of Obstetrics and Gynecology |
Volume | 207 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Jan 2012 |
Externally published | Yes |
Keywords
- preterm birth
- recurrence risk
- singleton pregnancy
- twin pregnancy