Recurrence of acoustic neurilemoma as a malignant spindle-cell neoplasm

C. A. McLean, J. D. Laidlaw, D. S.B. Brownbill, M. F. Gonzales

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A 75-year-old man presented with a right cerebellopontine angle tumor 11 months after complete macroscopic resection of a right acoustic neurilemoma. Histological examination of the recurrent tumor showed a malignant spindle-cell neoplasm with positive staining for S-100 protein. The patient has no stigmata of von Recklinghausen's disease. It is proposed that this recurrence represents progression from a benign to a malignant acoustic nerve-sheath tumor, an event that is extremely rare outside the clinicopathological context of neurofibromatosis.

Original languageEnglish
Pages (from-to)946-950
Number of pages5
JournalJournal of Neurosurgery
Issue number6
Publication statusPublished - 1990
Externally publishedYes


  • Acoustic neurinoma
  • Cerebellopontine angle tumor
  • Schwannoma

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