Recruiting people with HIV to an online self-management support randomised controlled trial

Barriers and facilitators

Karen M. Klassen, Tanya Millard, Julia Stout, Karalyn McDonald, Sarity Dodson, Richard H. Osborne, Malcolm W. Battersby, Christopher K. Fairley, Michael R. Kidd, James McMahon, David Baker, Julian H. Elliott

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Recruitment of people to randomised trials of online interventions presents particular challenges and opportunities. The aim of this study was to evaluate factors associated with the recruitment of people with HIV (PWHIV) and their doctors to the HealthMap trial, a cluster randomised trial of an online self-management program. Methods: Recruitment involved a three-step process. Study sites were recruited, followed by doctors caring for PWHIV at study sites and finally PWHIV. Data were collected from study sites, doctors and patient participants. Factors associated with site enrolment and patient participant recruitment were investigated using regression models. Results: Thirteen study sites, 63 doctor participants and 728 patient participants were recruited to the study. Doctors having a prior relationship with the study investigators (odds ratio (OR) 13.3 95% confidence interval (CI) 3.0, 58.7 P = 0.001) was positively associated with becoming a HealthMap site. Most patient participants successfully recruited to HealthMap (80%) had heard about the study from their HIV doctor. Patient enrolment was associated with the number of people with HIV receiving care at the site (β coefficient 0.10 95% CI 0.04, 0.16 P = 0.004), but not with employing a clinic or research nurse to help recruit patients (β coefficient 55.9 95% CI -2.55, 114.25 P = 0.06). Conclusion: Despite substantial investment in online promotion, a previous relationship with doctors was important for doctor recruitment, and doctors themselves were the most important source of patient recruitment to the HealthMap trial. Clinic-based recruitment strategies remain a critical component of trial recruitment, despite expanding opportunities to engage with online communities.

Original languageEnglish
Number of pages8
JournalSexual Health
DOIs
Publication statusAccepted/In press - Jun 2019

Keywords

  • clinical trial
  • recruitment

Cite this

Klassen, Karen M. ; Millard, Tanya ; Stout, Julia ; McDonald, Karalyn ; Dodson, Sarity ; Osborne, Richard H. ; Battersby, Malcolm W. ; Fairley, Christopher K. ; Kidd, Michael R. ; McMahon, James ; Baker, David ; Elliott, Julian H. / Recruiting people with HIV to an online self-management support randomised controlled trial : Barriers and facilitators. In: Sexual Health. 2019.
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abstract = "Background: Recruitment of people to randomised trials of online interventions presents particular challenges and opportunities. The aim of this study was to evaluate factors associated with the recruitment of people with HIV (PWHIV) and their doctors to the HealthMap trial, a cluster randomised trial of an online self-management program. Methods: Recruitment involved a three-step process. Study sites were recruited, followed by doctors caring for PWHIV at study sites and finally PWHIV. Data were collected from study sites, doctors and patient participants. Factors associated with site enrolment and patient participant recruitment were investigated using regression models. Results: Thirteen study sites, 63 doctor participants and 728 patient participants were recruited to the study. Doctors having a prior relationship with the study investigators (odds ratio (OR) 13.3 95{\%} confidence interval (CI) 3.0, 58.7 P = 0.001) was positively associated with becoming a HealthMap site. Most patient participants successfully recruited to HealthMap (80{\%}) had heard about the study from their HIV doctor. Patient enrolment was associated with the number of people with HIV receiving care at the site (β coefficient 0.10 95{\%} CI 0.04, 0.16 P = 0.004), but not with employing a clinic or research nurse to help recruit patients (β coefficient 55.9 95{\%} CI -2.55, 114.25 P = 0.06). Conclusion: Despite substantial investment in online promotion, a previous relationship with doctors was important for doctor recruitment, and doctors themselves were the most important source of patient recruitment to the HealthMap trial. Clinic-based recruitment strategies remain a critical component of trial recruitment, despite expanding opportunities to engage with online communities.",
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author = "Klassen, {Karen M.} and Tanya Millard and Julia Stout and Karalyn McDonald and Sarity Dodson and Osborne, {Richard H.} and Battersby, {Malcolm W.} and Fairley, {Christopher K.} and Kidd, {Michael R.} and James McMahon and David Baker and Elliott, {Julian H.}",
year = "2019",
month = "6",
doi = "10.1071/SH18130",
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Recruiting people with HIV to an online self-management support randomised controlled trial : Barriers and facilitators. / Klassen, Karen M.; Millard, Tanya; Stout, Julia; McDonald, Karalyn; Dodson, Sarity; Osborne, Richard H.; Battersby, Malcolm W.; Fairley, Christopher K.; Kidd, Michael R.; McMahon, James; Baker, David; Elliott, Julian H.

In: Sexual Health, 06.2019.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Recruiting people with HIV to an online self-management support randomised controlled trial

T2 - Barriers and facilitators

AU - Klassen, Karen M.

AU - Millard, Tanya

AU - Stout, Julia

AU - McDonald, Karalyn

AU - Dodson, Sarity

AU - Osborne, Richard H.

AU - Battersby, Malcolm W.

AU - Fairley, Christopher K.

AU - Kidd, Michael R.

AU - McMahon, James

AU - Baker, David

AU - Elliott, Julian H.

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Y1 - 2019/6

N2 - Background: Recruitment of people to randomised trials of online interventions presents particular challenges and opportunities. The aim of this study was to evaluate factors associated with the recruitment of people with HIV (PWHIV) and their doctors to the HealthMap trial, a cluster randomised trial of an online self-management program. Methods: Recruitment involved a three-step process. Study sites were recruited, followed by doctors caring for PWHIV at study sites and finally PWHIV. Data were collected from study sites, doctors and patient participants. Factors associated with site enrolment and patient participant recruitment were investigated using regression models. Results: Thirteen study sites, 63 doctor participants and 728 patient participants were recruited to the study. Doctors having a prior relationship with the study investigators (odds ratio (OR) 13.3 95% confidence interval (CI) 3.0, 58.7 P = 0.001) was positively associated with becoming a HealthMap site. Most patient participants successfully recruited to HealthMap (80%) had heard about the study from their HIV doctor. Patient enrolment was associated with the number of people with HIV receiving care at the site (β coefficient 0.10 95% CI 0.04, 0.16 P = 0.004), but not with employing a clinic or research nurse to help recruit patients (β coefficient 55.9 95% CI -2.55, 114.25 P = 0.06). Conclusion: Despite substantial investment in online promotion, a previous relationship with doctors was important for doctor recruitment, and doctors themselves were the most important source of patient recruitment to the HealthMap trial. Clinic-based recruitment strategies remain a critical component of trial recruitment, despite expanding opportunities to engage with online communities.

AB - Background: Recruitment of people to randomised trials of online interventions presents particular challenges and opportunities. The aim of this study was to evaluate factors associated with the recruitment of people with HIV (PWHIV) and their doctors to the HealthMap trial, a cluster randomised trial of an online self-management program. Methods: Recruitment involved a three-step process. Study sites were recruited, followed by doctors caring for PWHIV at study sites and finally PWHIV. Data were collected from study sites, doctors and patient participants. Factors associated with site enrolment and patient participant recruitment were investigated using regression models. Results: Thirteen study sites, 63 doctor participants and 728 patient participants were recruited to the study. Doctors having a prior relationship with the study investigators (odds ratio (OR) 13.3 95% confidence interval (CI) 3.0, 58.7 P = 0.001) was positively associated with becoming a HealthMap site. Most patient participants successfully recruited to HealthMap (80%) had heard about the study from their HIV doctor. Patient enrolment was associated with the number of people with HIV receiving care at the site (β coefficient 0.10 95% CI 0.04, 0.16 P = 0.004), but not with employing a clinic or research nurse to help recruit patients (β coefficient 55.9 95% CI -2.55, 114.25 P = 0.06). Conclusion: Despite substantial investment in online promotion, a previous relationship with doctors was important for doctor recruitment, and doctors themselves were the most important source of patient recruitment to the HealthMap trial. Clinic-based recruitment strategies remain a critical component of trial recruitment, despite expanding opportunities to engage with online communities.

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DO - 10.1071/SH18130

M3 - Article

JO - Sexual Health

JF - Sexual Health

SN - 1448-5028

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