Reconstructing the infected aortic root with antibiotic impregnated biological glue

David C. McGiffin, James E. Davies, James K. Kirklin

Research output: Contribution to journalArticleOtherpeer-review

2 Citations (Scopus)


Prosthetic valve dehiscence and persistent infection are two complications following reconstruction of the aortic root in destructive endocarditis. A technique is described involving the principles of aggressive debridement, closure of large abscess cavities with biological material incorporating a slurry of antibiotic-impregnated biological sealant, and replacement of the aortic valve with an aortic allograft valve. This strategy appears to have been successful in preventing persistent endocarditis and valve dehiscence in a limited number of patients.

Original languageEnglish
Pages (from-to)340-342
Number of pages3
JournalJournal of Cardiac Surgery
Issue number3
Publication statusPublished - 2014
Externally publishedYes

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