Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies

Yutaka Takebe; Huanan Liao; Saiki Hase; Rie Uenishi; Yue Li; Xiao Jie Li; Xiaoxu Han; Hong Shang; Adeeba Kamarulzaman; Naoki Yamamoto; Oliver G. Pybus; Kok Keng Tee

doi:10.1016/j.vaccine.2009.07.101

Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies

Yutaka Takebe, Huanan Liao, Saiki Hase, Rie Uenishi, Yue Li, Xiao Jie Li, Xiaoxu Han, Hong Shang, Adeeba Kamarulzaman, Naoki Yamamoto, Oliver G. Pybus, Kok Keng Tee

Research output: Contribution to journal › Article › Research › peer-review

49 Citations (Scopus)

Abstract

HIV-1 CRF07_BC and CRF08_BC are closely related circulating recombinant forms (CRFs) with serious public health consequences in China. The temporal and spatial dynamics of these CRFs were determined by estimating their times of divergence, using phylogenetic and Bayesian coalescent methods. Studies of the timelines of CRF07_BC and CRF08_BC trace the expansion of these strains back their origins to Yunnan province. The present study highlights the relevance of incorporating evolutionary and molecular epidemiological analyses into an in-depth understanding of the genesis of HIV epidemic, providing information for determining regional and global public health policies, including future vaccine strategies. Crown

Original language	English
Pages (from-to)	B39-B44
Number of pages	6
Journal	Vaccine
Volume	28
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1016/j.vaccine.2009.07.101
Publication status	Published - 26 May 2010
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

BEAST
Circulating recombinant form (CRF)
East Asia
HIV-1
Phylodynamics
Time of the most recent common ancestor (tMRCA)
Vaccine strategies

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10.1016/j.vaccine.2009.07.101

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Takebe, Y., Liao, H., Hase, S., Uenishi, R., Li, Y., Li, X. J., Han, X., Shang, H., Kamarulzaman, A., Yamamoto, N., Pybus, O. G., & Tee, K. K. (2010). Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies. Vaccine, 28(SUPPL. 2), B39-B44. https://doi.org/10.1016/j.vaccine.2009.07.101

@article{1c295073559649ec815572392ef6885a,

title = "Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07\_BC and CRF08\_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies",

abstract = "HIV-1 CRF07\_BC and CRF08\_BC are closely related circulating recombinant forms (CRFs) with serious public health consequences in China. The temporal and spatial dynamics of these CRFs were determined by estimating their times of divergence, using phylogenetic and Bayesian coalescent methods. Studies of the timelines of CRF07\_BC and CRF08\_BC trace the expansion of these strains back their origins to Yunnan province. The present study highlights the relevance of incorporating evolutionary and molecular epidemiological analyses into an in-depth understanding of the genesis of HIV epidemic, providing information for determining regional and global public health policies, including future vaccine strategies. Crown",

keywords = "BEAST, Circulating recombinant form (CRF), East Asia, HIV-1, Phylodynamics, Time of the most recent common ancestor (tMRCA), Vaccine strategies",

author = "Yutaka Takebe and Huanan Liao and Saiki Hase and Rie Uenishi and Yue Li and Li, \{Xiao Jie\} and Xiaoxu Han and Hong Shang and Adeeba Kamarulzaman and Naoki Yamamoto and Pybus, \{Oliver G.\} and Tee, \{Kok Keng\}",

note = "Funding Information: The authors gratefully acknowledge Tim Mastro and anonymous reviewers for critical reading of manuscript. This study was supported in part by grants from the Ministry of Health, Labour \& Welfare ( H18-AIDS-General-016 ), Ministry of Education, Culture, Sports, Science and Technology (Overseas Research Fund) to Y.T., and the Japanese Foundation for AIDS Prevention (JFAP), and the Ministry of Science, Technology \& Innovation (eScienceFund 02-01-03-SF0379 , Malaysia) to A. K.; and the Royal Society International Project Fund to O.G.P. and Y.T. K.K.T., H.L., and R.U. are recipients of the JFAP research resident fellowship. S.H. is a recipient of the research resident fellowship from the Human Sciences Foundation.",

year = "2010",

month = may,

day = "26",

doi = "10.1016/j.vaccine.2009.07.101",

language = "English",

volume = "28",

pages = "B39--B44",

journal = "Vaccine",

issn = "0264-410X",

publisher = "Elsevier",

number = "SUPPL. 2",

}

Takebe, Y, Liao, H, Hase, S, Uenishi, R, Li, Y, Li, XJ, Han, X, Shang, H, Kamarulzaman, A, Yamamoto, N, Pybus, OG & Tee, KK 2010, 'Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies', Vaccine, vol. 28, no. SUPPL. 2, pp. B39-B44. https://doi.org/10.1016/j.vaccine.2009.07.101

Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies. / Takebe, Yutaka; Liao, Huanan; Hase, Saiki et al.
In: Vaccine, Vol. 28, No. SUPPL. 2, 26.05.2010, p. B39-B44.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia

T2 - The relevance of genetic diversity and phylodynamics for vaccine strategies

AU - Takebe, Yutaka

AU - Liao, Huanan

AU - Hase, Saiki

AU - Uenishi, Rie

AU - Li, Yue

AU - Li, Xiao Jie

AU - Han, Xiaoxu

AU - Shang, Hong

AU - Kamarulzaman, Adeeba

AU - Yamamoto, Naoki

AU - Pybus, Oliver G.

AU - Tee, Kok Keng

N1 - Funding Information: The authors gratefully acknowledge Tim Mastro and anonymous reviewers for critical reading of manuscript. This study was supported in part by grants from the Ministry of Health, Labour & Welfare ( H18-AIDS-General-016 ), Ministry of Education, Culture, Sports, Science and Technology (Overseas Research Fund) to Y.T., and the Japanese Foundation for AIDS Prevention (JFAP), and the Ministry of Science, Technology & Innovation (eScienceFund 02-01-03-SF0379 , Malaysia) to A. K.; and the Royal Society International Project Fund to O.G.P. and Y.T. K.K.T., H.L., and R.U. are recipients of the JFAP research resident fellowship. S.H. is a recipient of the research resident fellowship from the Human Sciences Foundation.

PY - 2010/5/26

Y1 - 2010/5/26

N2 - HIV-1 CRF07_BC and CRF08_BC are closely related circulating recombinant forms (CRFs) with serious public health consequences in China. The temporal and spatial dynamics of these CRFs were determined by estimating their times of divergence, using phylogenetic and Bayesian coalescent methods. Studies of the timelines of CRF07_BC and CRF08_BC trace the expansion of these strains back their origins to Yunnan province. The present study highlights the relevance of incorporating evolutionary and molecular epidemiological analyses into an in-depth understanding of the genesis of HIV epidemic, providing information for determining regional and global public health policies, including future vaccine strategies. Crown

AB - HIV-1 CRF07_BC and CRF08_BC are closely related circulating recombinant forms (CRFs) with serious public health consequences in China. The temporal and spatial dynamics of these CRFs were determined by estimating their times of divergence, using phylogenetic and Bayesian coalescent methods. Studies of the timelines of CRF07_BC and CRF08_BC trace the expansion of these strains back their origins to Yunnan province. The present study highlights the relevance of incorporating evolutionary and molecular epidemiological analyses into an in-depth understanding of the genesis of HIV epidemic, providing information for determining regional and global public health policies, including future vaccine strategies. Crown

KW - BEAST

KW - Circulating recombinant form (CRF)

KW - East Asia

KW - HIV-1

KW - Phylodynamics

KW - Time of the most recent common ancestor (tMRCA)

KW - Vaccine strategies

UR - https://www.scopus.com/pages/publications/77952488506

U2 - 10.1016/j.vaccine.2009.07.101

DO - 10.1016/j.vaccine.2009.07.101

M3 - Article

C2 - 20510742

AN - SCOPUS:77952488506

SN - 0264-410X

VL - 28

SP - B39-B44

JO - Vaccine

JF - Vaccine

IS - SUPPL. 2

ER -

Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: The relevance of genetic diversity and phylodynamics for vaccine strategies

Abstract

UN SDGs

Keywords

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