Recent advances in magnetic nanoparticle-based molecular probes for hepatocellular carcinoma diagnosis and therapy

Qi Zhang, Sudan Wang, Ruirui Qiao, Michael R. Whittaker, John F. Quinn, Thomas P. Davis, Hongjun Li

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, leading to the second most likely cause of cancer-related deaths. Medical imaging is crucial in clinic for HCC screening and diagnosis. Due to the relatively high special resolution and excellent sensitivity, magnetic resonance imaging (MRI) by using magnetic nanoparticle-based contrast agents has been used so far in HCC imaging and staging, demonstrating great potential and promising in vivo applications. This review focuses on the use of different magnetic nanoparticles for construction of HCC nanoprobes for MR imaging and theranostic purpose.

Original languageEnglish
Pages (from-to)2432-2437
Number of pages6
JournalCurrent Pharmaceutical Design
Volume24
Issue number21
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Cancer
  • Diagnosis
  • Hepatocellular carcinoma
  • Magnetic nanoparticle
  • Molecular imaging
  • Mri

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