Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation

Research output: Contribution to journalComment / DebateOtherpeer-review

Abstract

LC3/GABARAP (hereafter ATG8) conjugation machineries have long been thought to play an essential role in autophagy by driving ATG8 lipidation on autophagosomal membranes. In this issue, Ohnstad et al (2020) describe an ATG8 lipidation bypass pathway which governs autophagy-dependent turnover of NBR1, highlighting that there is more than one road to autophagic degradation.

Original languageEnglish
Article numbere106990
Number of pages2
JournalEMBO Journal
Volume39
Issue number24
DOIs
Publication statusPublished - 15 Dec 2020

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