Reading on the right when there’s nothing left? Probabilistic tractography reveals hemispheric asymmetry in pure alexia

Michele Veldsman, Tobias Loetscher, Amanda Wood, Amy Brodtmann

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

We present a patient with reading inexpertise and right hemianopia following left posterior cerebral artery (PCA) stroke. We examine the extent of disruption to reading performance and the extent of white matter tract damage relative to a patient with more limited PCA infarction and isolated right hemianopia. We show white matter disconnection of the temporal occipital fusiform cortex in our pure alexia patient. Connectivity-based laterality indices revealed right hemisphere laterality in the alexia patient; this was not associated with improved reading function. We speculate that the degree of premorbid laterality may be a critical factor affecting the extent of reading dysfunction in alexia.

Original languageEnglish
Pages (from-to)201-209
Number of pages9
JournalNeurocase
Volume23
Issue number3-4
DOIs
Publication statusPublished - Aug 2017
Externally publishedYes

Keywords

  • alexia
  • diffusion tractography
  • Reading
  • stroke

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