Reactions catalyzed by bacterial cytochromes P450

Max J. Cryle, Jeanette E. Stok, James J. De Voss

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The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C-C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.

Original languageEnglish
Pages (from-to)749-762
Number of pages14
JournalAustralian Journal of Chemistry
Issue number8
Publication statusPublished - 2003
Externally publishedYes

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