Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer

Nikhil Sapre; John S Pedersen; Matthew K Hong; Laurence Milner Harewood; Justin Peters; Anthony J Costello; Christopher M Hovens; Niall M Corcoran

doi:10.1111/j.1464-410X.2012.11477.x

Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer

Nikhil Sapre, John S Pedersen, Matthew K Hong, Laurence Milner Harewood, Justin Peters, Anthony J Costello, Christopher M Hovens, Niall M Corcoran

Hudson Institute - Department of Molecular and Translational Science

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Abstract

To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. To explore the clinical association of SVI with metastatic disease. To distinguish between the possibilities that either seminal vesicles possess their own biological significance and represent a privileged staging site for systemic tumour cell dissemination, or that their invasion is a surrogate marker for an aggressive large-volume poorly differentiated cancer.

Original language	English
Pages (from-to)	58 - 63
Number of pages	6
Journal	BJU International
Volume	110
Issue number	Supp 4
DOIs	https://doi.org/10.1111/j.1464-410X.2012.11477.x
Publication status	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1464-410X.2012.11477.x

Cite this

@article{a26109d087ed4bffb477e65dfda54831,

title = "Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer",

abstract = "To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. To explore the clinical association of SVI with metastatic disease. To distinguish between the possibilities that either seminal vesicles possess their own biological significance and represent a privileged staging site for systemic tumour cell dissemination, or that their invasion is a surrogate marker for an aggressive large-volume poorly differentiated cancer.",

author = "Nikhil Sapre and Pedersen, {John S} and Hong, {Matthew K} and Harewood, {Laurence Milner} and Justin Peters and Costello, {Anthony J} and Hovens, {Christopher M} and Corcoran, {Niall M}",

year = "2012",

doi = "10.1111/j.1464-410X.2012.11477.x",

language = "English",

volume = "110",

pages = "58 -- 63",

journal = "BJU International",

issn = "1464-4096",

publisher = "Wiley-Blackwell",

number = "Supp 4",

}

TY - JOUR

T1 - Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer

AU - Sapre, Nikhil

AU - Pedersen, John S

AU - Hong, Matthew K

AU - Harewood, Laurence Milner

AU - Peters, Justin

AU - Costello, Anthony J

AU - Hovens, Christopher M

AU - Corcoran, Niall M

PY - 2012

Y1 - 2012

N2 - To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. To explore the clinical association of SVI with metastatic disease. To distinguish between the possibilities that either seminal vesicles possess their own biological significance and represent a privileged staging site for systemic tumour cell dissemination, or that their invasion is a surrogate marker for an aggressive large-volume poorly differentiated cancer.

AB - To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. To explore the clinical association of SVI with metastatic disease. To distinguish between the possibilities that either seminal vesicles possess their own biological significance and represent a privileged staging site for systemic tumour cell dissemination, or that their invasion is a surrogate marker for an aggressive large-volume poorly differentiated cancer.

UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.11477.x/pdf

U2 - 10.1111/j.1464-410X.2012.11477.x

DO - 10.1111/j.1464-410X.2012.11477.x

M3 - Article

SN - 1464-4096

VL - 110

SP - 58

EP - 63

JO - BJU International

JF - BJU International

IS - Supp 4

ER -

Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer

Abstract

UN SDGs

Access to Document

Other files and links

Cite this