Rapid blood pressure lowering in acute intracerebral haemorrhage

Craig S Anderson; Emma L Heeley; Yining Huang; Ji-Guang Wang; Christian Stapf; Candice Delcourt; Richard I Lindley; Thompson G Robinson; Pablo M Lavados; Bruce Neal; Jun Hata; Hisatomi Arima; Mark W Parsons; Yuechun Li; Jinchao Wang; Stephane Roland Heritier; Qiang Li; Mark Woodward; R John Simes; Stephen M Davis; John P Chalmers

doi:10.1056/NEJMoa1214609

Rapid blood pressure lowering in acute intracerebral haemorrhage

Craig S Anderson, Emma L Heeley, Yining Huang, Ji-Guang Wang, Christian Stapf, Candice Delcourt, Richard I Lindley, Thompson G Robinson, Pablo M Lavados, Bruce Neal, Jun Hata, Hisatomi Arima, Mark W Parsons, Yuechun Li, Jinchao Wang, Stephane Roland Heritier, Qiang Li, Mark Woodward, R John Simes, Stephen M DavisJohn P Chalmers

Research output: Contribution to journal › Article › Research › peer-review

1255 Citations (Scopus)

Abstract

Background Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of

Original language	English
Pages (from-to)	2355 - 2365
Number of pages	11
Journal	The New England Journal of Medicine
Volume	368
Issue number	25
DOIs	https://doi.org/10.1056/NEJMoa1214609
Publication status	Published - 2013
Externally published	Yes

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10.1056/NEJMoa1214609

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Anderson, C. S., Heeley, E. L., Huang, Y., Wang, J.-G., Stapf, C., Delcourt, C., Lindley, R. I., Robinson, T. G., Lavados, P. M., Neal, B., Hata, J., Arima, H., Parsons, M. W., Li, Y., Wang, J., Heritier, S. R., Li, Q., Woodward, M., Simes, R. J., ... Chalmers, J. P. (2013). Rapid blood pressure lowering in acute intracerebral haemorrhage. The New England Journal of Medicine, 368(25), 2355 - 2365. https://doi.org/10.1056/NEJMoa1214609

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abstract = "Background Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of",

author = "Anderson, {Craig S} and Heeley, {Emma L} and Yining Huang and Ji-Guang Wang and Christian Stapf and Candice Delcourt and Lindley, {Richard I} and Robinson, {Thompson G} and Lavados, {Pablo M} and Bruce Neal and Jun Hata and Hisatomi Arima and Parsons, {Mark W} and Yuechun Li and Jinchao Wang and Heritier, {Stephane Roland} and Qiang Li and Mark Woodward and Simes, {R John} and Davis, {Stephen M} and Chalmers, {John P}",

year = "2013",

doi = "10.1056/NEJMoa1214609",

language = "English",

volume = "368",

pages = "2355 -- 2365",

journal = "The New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

number = "25",

}

Anderson, CS, Heeley, EL, Huang, Y, Wang, J-G, Stapf, C, Delcourt, C, Lindley, RI, Robinson, TG, Lavados, PM, Neal, B, Hata, J, Arima, H, Parsons, MW, Li, Y, Wang, J, Heritier, SR, Li, Q, Woodward, M, Simes, RJ, Davis, SM & Chalmers, JP 2013, 'Rapid blood pressure lowering in acute intracerebral haemorrhage', The New England Journal of Medicine, vol. 368, no. 25, pp. 2355 - 2365. https://doi.org/10.1056/NEJMoa1214609

TY - JOUR

T1 - Rapid blood pressure lowering in acute intracerebral haemorrhage

AU - Anderson, Craig S

AU - Heeley, Emma L

AU - Huang, Yining

AU - Wang, Ji-Guang

AU - Stapf, Christian

AU - Delcourt, Candice

AU - Lindley, Richard I

AU - Robinson, Thompson G

AU - Lavados, Pablo M

AU - Neal, Bruce

AU - Hata, Jun

AU - Arima, Hisatomi

AU - Parsons, Mark W

AU - Li, Yuechun

AU - Wang, Jinchao

AU - Heritier, Stephane Roland

AU - Li, Qiang

AU - Woodward, Mark

AU - Simes, R John

AU - Davis, Stephen M

AU - Chalmers, John P

PY - 2013

Y1 - 2013

N2 - Background Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of

AB - Background Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of

UR - http://www.nejm.org/doi/pdf/10.1056/NEJMoa1214609

U2 - 10.1056/NEJMoa1214609

DO - 10.1056/NEJMoa1214609

M3 - Article

SN - 0028-4793

VL - 368

SP - 2355

EP - 2365

JO - The New England Journal of Medicine

JF - The New England Journal of Medicine

IS - 25

ER -

Rapid blood pressure lowering in acute intracerebral haemorrhage

Abstract

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