Rapid adaptation induces persistent biases in population codes for visual motion

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Each visual experience changes the neural response to subsequent stimuli. If the brain is unable to incorporate these encoding changes, the decoding, or perception, of subsequent stimuli is biased. Although the phenomenon of adaptation pervades the nervous system, its effects have been studied mainly in isolation, based on neuronal encoding changes induced by an isolated, prolonged stimulus. To understand how adaptation-induced biases arise and persist under continuous, naturalistic stimulation, we simultaneously recorded the responses of up to 61 neurons in the marmoset (Callithrix jacchus) middle temporal area to a sequence of directions that changed every 500 ms. We found that direction-specific adaptation following only 0.5 s of stimulation strongly affected encoding for up to 2 s by reducing both the gain and the spike count correlations between pairs of neurons with preferred directions close to the adapting direction. In addition, smaller changes in bandwidth and preferred direction were observed in some animals. Decoding individual trials of adaptation-affected activity in simultaneously recorded neurons predicted repulsive biases that are consistent with the direction aftereffect. Surprisingly, removing spike count correlations by trial shuffling did not impact decoding performance or bias. When adaptation had the largest effect on encoding, the decoder made the most errors. This suggests that neural and perceptual repulsion is not a mechanism to enhance perceptual performance but is instead a necessary consequence of optimizing neural encoding for the identification of a wide range of stimulus properties in diverse temporal contexts.
Original languageEnglish
Pages (from-to)4579-4590
Number of pages12
JournalJournal of Neuroscience
Volume36
Issue number16
DOIs
Publication statusPublished - 20 Apr 2016

Keywords

  • adaptation
  • area MT
  • direction aftereffect
  • marmoset
  • middle temporal area
  • motion

Cite this

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title = "Rapid adaptation induces persistent biases in population codes for visual motion",
abstract = "Each visual experience changes the neural response to subsequent stimuli. If the brain is unable to incorporate these encoding changes, the decoding, or perception, of subsequent stimuli is biased. Although the phenomenon of adaptation pervades the nervous system, its effects have been studied mainly in isolation, based on neuronal encoding changes induced by an isolated, prolonged stimulus. To understand how adaptation-induced biases arise and persist under continuous, naturalistic stimulation, we simultaneously recorded the responses of up to 61 neurons in the marmoset (Callithrix jacchus) middle temporal area to a sequence of directions that changed every 500 ms. We found that direction-specific adaptation following only 0.5 s of stimulation strongly affected encoding for up to 2 s by reducing both the gain and the spike count correlations between pairs of neurons with preferred directions close to the adapting direction. In addition, smaller changes in bandwidth and preferred direction were observed in some animals. Decoding individual trials of adaptation-affected activity in simultaneously recorded neurons predicted repulsive biases that are consistent with the direction aftereffect. Surprisingly, removing spike count correlations by trial shuffling did not impact decoding performance or bias. When adaptation had the largest effect on encoding, the decoder made the most errors. This suggests that neural and perceptual repulsion is not a mechanism to enhance perceptual performance but is instead a necessary consequence of optimizing neural encoding for the identification of a wide range of stimulus properties in diverse temporal contexts.",
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author = "Elizabeth Zavitz and Hsin-Hao Yu and Rowe, {Elise G.} and Rosa, {Marcello G.P.} and Price, {Nicholas S. C.}",
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Rapid adaptation induces persistent biases in population codes for visual motion. / Zavitz, Elizabeth; Yu, Hsin-Hao; Rowe, Elise G.; Rosa, Marcello G.P.; Price, Nicholas S. C.

In: Journal of Neuroscience, Vol. 36, No. 16, 20.04.2016, p. 4579-4590.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Rapid adaptation induces persistent biases in population codes for visual motion

AU - Zavitz, Elizabeth

AU - Yu, Hsin-Hao

AU - Rowe, Elise G.

AU - Rosa, Marcello G.P.

AU - Price, Nicholas S. C.

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