Abstract
This study compared the effectiveness of concentrated (2 mg/ml) i.n. naloxone to intramuscular (i.m.) naloxone for suspected opiate overdose. Methods This randomized controlled trial included patients treated for suspected opiate overdose in the pre-hospital setting. Patients received 2 mg of either i.n. or i.m. naloxone. The primary outcome was the proportion of patients who responded within 10 minutes of naloxone treatment. Secondary outcomes included time to adequate response and requirement for supplementary naloxone. Data were analysed usingmultivariate statistical techniques.
Original language | English |
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Pages (from-to) | 2067 - 2074 |
Number of pages | 8 |
Journal | Addiction |
Volume | 104 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2009 |