Radicals and transition-metal catalysis: An alliance par excellence to increase reactivity and selectivity in organic chemistry

Leigh Ford, Ullrich Jahn

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Abstract

Welcome to radical catalysis: Radicals are tamed in transition-metal complexes which serve as catalysts for a number of reactions - Kumada couplings (see scheme), highly regioselective cobalt-catalyzed eliminations, Markovnikov additions, and reductive epoxide openings catalyzed by a titanium/rhodium system. All of these reactions are powered by the high reactivity of radical intermediates in the catalytic cycle of the metal-catalyzed process.
Original languageEnglish
Pages (from-to)6386 - 6389
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number35
DOIs
Publication statusPublished - 2009
Externally publishedYes

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