“Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services: study protocol

Amanda L. Baker, Ronald Borland, Billie Bonevski, Catherine Segan, Alyna Turner, Lisa Brophy, Kristen McCarter, Peter J Kelly, Jill M Williams, Donita Baird, John Attia, Rohan Sweeney, Sarah L White, Sacha Filia, David Castle

Research output: Contribution to journalArticleOtherpeer-review

Abstract

Introduction: Although smokers with severe mental illnesses (SSMI) make quit attempts at comparable levels to other smokers, fewer are successful in achieving smoking cessation. Specialized smoking cessation treatments targeting their needs can be effective but have not been widely disseminated. Telephone delivered interventions, including by quitlines, show promise. However, few SSMI contact quitlines and few are referred to them by health professionals. Mental health peer workers can potentially play an important role in supporting smoking cessation. This study will apply a pragmatic model using peer workers to engage SSMI with a customized quitline service, forming the “Quitlink” intervention.

Methods: A multi-center prospective, cluster-randomized, open, blinded endpoint (PROBE) trial. Over 3 years, 382 smokers will be recruited from mental health services in Victoria, Australia. Following completion of baseline assessment, a brief intervention will be delivered by a peer worker. Participants will then be randomly allocated either to no further intervention, or to be referred and contacted by the Victorian Quitline and offered a targeted 8-week cognitive behavioral intervention along with nicotine replacement therapy (NRT). Follow-up measures will be administered at 2-, 5-, and 8-months post-baseline. The primary outcome is 6 months continuous abstinence from end of treatment with biochemical verification. Secondary outcomes include 7-day point prevalence abstinence from smoking, increased quit attempts, and reductions in cigarettes per day, cravings and withdrawal, mental health symptoms, and other substance use, and improvements in quality of life. We will use a generalized linear mixed model (linear regression for continuous outcomes and logistic regression for dichotomous outcomes) to handle clustering and the repeated measures at baseline, 2-, 5-, and 8-months; individuals will be modeled as random effects, cluster as a random effect, and group assignment as a fixed effect.

Discussion: This is the first rigorously designed RCT to evaluate a specialized quitline intervention accompanied by NRT among SSMI. The study will apply a pragmatic model to link SSMI to the Quitline, using peer workers, with the potential for wide dissemination.

Clinical Trial Registration:
Trial Registry: The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN12619000244101 prior to the accrual of the first participant and updated regularly as per registry guidelines.

Trial Sponsor: University of Newcastle, NSW, Australia.
Original languageEnglish
Article number124
Number of pages15
JournalFrontiers in Psychiatry
Volume10
DOIs
Publication statusPublished - Mar 2019

Keywords

  • smoking
  • smoking cessation
  • Quitline
  • peer worker
  • mental illness
  • severe mental illness
  • psychosis

Cite this

Baker, Amanda L. ; Borland, Ronald ; Bonevski, Billie ; Segan, Catherine ; Turner, Alyna ; Brophy, Lisa ; McCarter, Kristen ; Kelly, Peter J ; Williams, Jill M ; Baird, Donita ; Attia, John ; Sweeney, Rohan ; White, Sarah L ; Filia, Sacha ; Castle, David. / “Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services : study protocol. In: Frontiers in Psychiatry. 2019 ; Vol. 10.
@article{036f016acb7c437e9c3b70f156911c4e,
title = "“Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services: study protocol",
abstract = "Introduction: Although smokers with severe mental illnesses (SSMI) make quit attempts at comparable levels to other smokers, fewer are successful in achieving smoking cessation. Specialized smoking cessation treatments targeting their needs can be effective but have not been widely disseminated. Telephone delivered interventions, including by quitlines, show promise. However, few SSMI contact quitlines and few are referred to them by health professionals. Mental health peer workers can potentially play an important role in supporting smoking cessation. This study will apply a pragmatic model using peer workers to engage SSMI with a customized quitline service, forming the “Quitlink” intervention.Methods: A multi-center prospective, cluster-randomized, open, blinded endpoint (PROBE) trial. Over 3 years, 382 smokers will be recruited from mental health services in Victoria, Australia. Following completion of baseline assessment, a brief intervention will be delivered by a peer worker. Participants will then be randomly allocated either to no further intervention, or to be referred and contacted by the Victorian Quitline and offered a targeted 8-week cognitive behavioral intervention along with nicotine replacement therapy (NRT). Follow-up measures will be administered at 2-, 5-, and 8-months post-baseline. The primary outcome is 6 months continuous abstinence from end of treatment with biochemical verification. Secondary outcomes include 7-day point prevalence abstinence from smoking, increased quit attempts, and reductions in cigarettes per day, cravings and withdrawal, mental health symptoms, and other substance use, and improvements in quality of life. We will use a generalized linear mixed model (linear regression for continuous outcomes and logistic regression for dichotomous outcomes) to handle clustering and the repeated measures at baseline, 2-, 5-, and 8-months; individuals will be modeled as random effects, cluster as a random effect, and group assignment as a fixed effect.Discussion: This is the first rigorously designed RCT to evaluate a specialized quitline intervention accompanied by NRT among SSMI. The study will apply a pragmatic model to link SSMI to the Quitline, using peer workers, with the potential for wide dissemination.Clinical Trial Registration:Trial Registry: The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN12619000244101 prior to the accrual of the first participant and updated regularly as per registry guidelines.Trial Sponsor: University of Newcastle, NSW, Australia.",
keywords = "smoking, smoking cessation, Quitline, peer worker, mental illness, severe mental illness, psychosis",
author = "Baker, {Amanda L.} and Ronald Borland and Billie Bonevski and Catherine Segan and Alyna Turner and Lisa Brophy and Kristen McCarter and Kelly, {Peter J} and Williams, {Jill M} and Donita Baird and John Attia and Rohan Sweeney and White, {Sarah L} and Sacha Filia and David Castle",
year = "2019",
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Baker, AL, Borland, R, Bonevski, B, Segan, C, Turner, A, Brophy, L, McCarter, K, Kelly, PJ, Williams, JM, Baird, D, Attia, J, Sweeney, R, White, SL, Filia, S & Castle, D 2019, '“Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services: study protocol' Frontiers in Psychiatry, vol. 10, 124. https://doi.org/10.3389/fpsyt.2019.00124

“Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services : study protocol. / Baker, Amanda L.; Borland, Ronald; Bonevski, Billie; Segan, Catherine; Turner, Alyna; Brophy, Lisa; McCarter, Kristen; Kelly, Peter J; Williams, Jill M; Baird, Donita; Attia, John ; Sweeney, Rohan; White, Sarah L; Filia, Sacha; Castle, David.

In: Frontiers in Psychiatry, Vol. 10, 124, 03.2019.

Research output: Contribution to journalArticleOtherpeer-review

TY - JOUR

T1 - “Quitlink” - a randomized controlled trial of peer worker facilitated Quitline support for smokers receiving mental health services

T2 - study protocol

AU - Baker, Amanda L.

AU - Borland, Ronald

AU - Bonevski, Billie

AU - Segan, Catherine

AU - Turner, Alyna

AU - Brophy, Lisa

AU - McCarter, Kristen

AU - Kelly, Peter J

AU - Williams, Jill M

AU - Baird, Donita

AU - Attia, John

AU - Sweeney, Rohan

AU - White, Sarah L

AU - Filia, Sacha

AU - Castle, David

PY - 2019/3

Y1 - 2019/3

N2 - Introduction: Although smokers with severe mental illnesses (SSMI) make quit attempts at comparable levels to other smokers, fewer are successful in achieving smoking cessation. Specialized smoking cessation treatments targeting their needs can be effective but have not been widely disseminated. Telephone delivered interventions, including by quitlines, show promise. However, few SSMI contact quitlines and few are referred to them by health professionals. Mental health peer workers can potentially play an important role in supporting smoking cessation. This study will apply a pragmatic model using peer workers to engage SSMI with a customized quitline service, forming the “Quitlink” intervention.Methods: A multi-center prospective, cluster-randomized, open, blinded endpoint (PROBE) trial. Over 3 years, 382 smokers will be recruited from mental health services in Victoria, Australia. Following completion of baseline assessment, a brief intervention will be delivered by a peer worker. Participants will then be randomly allocated either to no further intervention, or to be referred and contacted by the Victorian Quitline and offered a targeted 8-week cognitive behavioral intervention along with nicotine replacement therapy (NRT). Follow-up measures will be administered at 2-, 5-, and 8-months post-baseline. The primary outcome is 6 months continuous abstinence from end of treatment with biochemical verification. Secondary outcomes include 7-day point prevalence abstinence from smoking, increased quit attempts, and reductions in cigarettes per day, cravings and withdrawal, mental health symptoms, and other substance use, and improvements in quality of life. We will use a generalized linear mixed model (linear regression for continuous outcomes and logistic regression for dichotomous outcomes) to handle clustering and the repeated measures at baseline, 2-, 5-, and 8-months; individuals will be modeled as random effects, cluster as a random effect, and group assignment as a fixed effect.Discussion: This is the first rigorously designed RCT to evaluate a specialized quitline intervention accompanied by NRT among SSMI. The study will apply a pragmatic model to link SSMI to the Quitline, using peer workers, with the potential for wide dissemination.Clinical Trial Registration:Trial Registry: The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN12619000244101 prior to the accrual of the first participant and updated regularly as per registry guidelines.Trial Sponsor: University of Newcastle, NSW, Australia.

AB - Introduction: Although smokers with severe mental illnesses (SSMI) make quit attempts at comparable levels to other smokers, fewer are successful in achieving smoking cessation. Specialized smoking cessation treatments targeting their needs can be effective but have not been widely disseminated. Telephone delivered interventions, including by quitlines, show promise. However, few SSMI contact quitlines and few are referred to them by health professionals. Mental health peer workers can potentially play an important role in supporting smoking cessation. This study will apply a pragmatic model using peer workers to engage SSMI with a customized quitline service, forming the “Quitlink” intervention.Methods: A multi-center prospective, cluster-randomized, open, blinded endpoint (PROBE) trial. Over 3 years, 382 smokers will be recruited from mental health services in Victoria, Australia. Following completion of baseline assessment, a brief intervention will be delivered by a peer worker. Participants will then be randomly allocated either to no further intervention, or to be referred and contacted by the Victorian Quitline and offered a targeted 8-week cognitive behavioral intervention along with nicotine replacement therapy (NRT). Follow-up measures will be administered at 2-, 5-, and 8-months post-baseline. The primary outcome is 6 months continuous abstinence from end of treatment with biochemical verification. Secondary outcomes include 7-day point prevalence abstinence from smoking, increased quit attempts, and reductions in cigarettes per day, cravings and withdrawal, mental health symptoms, and other substance use, and improvements in quality of life. We will use a generalized linear mixed model (linear regression for continuous outcomes and logistic regression for dichotomous outcomes) to handle clustering and the repeated measures at baseline, 2-, 5-, and 8-months; individuals will be modeled as random effects, cluster as a random effect, and group assignment as a fixed effect.Discussion: This is the first rigorously designed RCT to evaluate a specialized quitline intervention accompanied by NRT among SSMI. The study will apply a pragmatic model to link SSMI to the Quitline, using peer workers, with the potential for wide dissemination.Clinical Trial Registration:Trial Registry: The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN12619000244101 prior to the accrual of the first participant and updated regularly as per registry guidelines.Trial Sponsor: University of Newcastle, NSW, Australia.

KW - smoking

KW - smoking cessation

KW - Quitline

KW - peer worker

KW - mental illness

KW - severe mental illness

KW - psychosis

U2 - 10.3389/fpsyt.2019.00124

DO - 10.3389/fpsyt.2019.00124

M3 - Article

VL - 10

JO - Frontiers in Psychiatry

JF - Frontiers in Psychiatry

SN - 1664-0640

M1 - 124

ER -