Quantitative assessment of corpus callosum morphology in periventricular nodular heterotopia

Heath R. Pardoe, Simone A. Mandelstam, Rebecca Kucharsky Hiess, Ruben I. Kuzniecky, Graeme D. Jackson

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12 Citations (Scopus)


We investigated systematic differences in corpus callosum morphology in periventricular nodular heterotopia (PVNH). Differences in corpus callosum mid-sagittal area and subregional area changes were measured using an automated software-based method. Heterotopic gray matter deposits were automatically labeled and compared with corpus callosum changes. The spatial pattern of corpus callosum changes were interpreted in the context of the characteristic anterior-posterior development of the corpus callosum in healthy individuals.

Original languageEnglish
Pages (from-to)40-47
Number of pages8
JournalEpilepsy Research
Issue number1
Publication statusPublished - 1 Jan 2015
Externally publishedYes


  • Brain development
  • Epilepsy
  • MRI
  • Neuroimaging

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