Quantitative assessment of cerebella ataxia through automated upper limb functional tests

Ragil Krishna, Pubudu N. Pathirana, Malcolm Horne, Laura Power, David Szmulewicz

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

2 Citations (Scopus)


Neurological disorders typically exhibit movement disabilities and disorders such as cerebellar ataxia (CA) can cause coordination inaccuracies often manifested as disabilities associated with gait, balance and speech. Since the severity assessment of the disorder is based on the expert clinical opinion, it is likely to be subjective. Automated versions of two upper limb tests: Finger to Nose test (FNT) and Diadochokinesia (DDK) test are investigated in this paper. Inertial Measurement Units (IMU) (BioKinTM) are employed to capture the disability by measuring limb movements. Translational and rotational accelerations considered as kinematic parameters provided the features relevant to characteristic movements intrinsic to the disability. Principal Component Analysis (PCA) and multi-class Linear Discriminant classifier (LDA) were instrumental in dominant features correlating with the clinical scores. The relationship between clinicians assessment and the objective analysis is examined using Pearson Correlation. This study found that although FNT predominantly consist of translational movements, rotation was the dominant feature while for the case of DDK that predominantly consist of rotational movements, acceleration was the dominant feature. The degree of correlation in each test was also enhanced by combining the features in different tests.

Original languageEnglish
Title of host publicationTenth International Conference on Signal Processing Systems
EditorsKezhi Mao, Xudong Jiang
PublisherSPIE - International Society for Optical Engineering
Number of pages7
ISBN (Electronic)9781510628366
ISBN (Print)9781510628359
Publication statusPublished - 1 Jan 2019
Externally publishedYes
EventInternational Conference on Signal Processing Systems 2018 - Singapore, Singapore
Duration: 16 Nov 201818 Nov 2018
Conference number: 10

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


ConferenceInternational Conference on Signal Processing Systems 2018


  • Diadochokinesia (DDK)
  • Fast fourier transforms (FFT)
  • Finger-to-Nose (FNT)
  • Linear dicriminant analysis (LDA)

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