Quantitative Assessment of Ataxic Gait using Inertial Sensing at Different Walking Speeds

Dung Phan, Nhan Nguyen, Pubudu N. Pathirana, Malcolm Horne, Laura Power, David Szmulewicz

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

2 Citations (Scopus)

Abstract

In this study, we employed wearable sensor technology to identify the kinematic features that are associated with the gait abnormalities seen in cerebellar ataxia. Measurements were made at self-selected slow, preferred and fast walking speeds with three sensors attached to the participant's body. Velocity irregularity and resonant frequency characteristics were identified as key features of interest concerning truncal and lower limb movements. Using the principal component analysis, differentiating features of both trunk and lower limb movements were combined to produce an enhanced distinction between the patients and the normal subjects, in addition to obtaining a better correlation with the expert clinician's assessments. The different speed of walking contributed to separation and correlation with medical severity rating scales such as SARA to varying degrees The results of truncal movement in the medio-lateral plane (at the slow gait speed) and antero-posterior movement (at all 3 gait speeds) provided the effective metrics in the diagnosis and severity rating of ataxic gait of CA patients. Furthermore, from the selected dominant features of the trunk and lower limb, principal component description suggested that overall clinical assessments are predominantly influenced by the lower body peripheral movements particularly at higher walking speeds.

Original languageEnglish
Title of host publication2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
EditorsRiccardo Barbieri
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages4600-4603
Number of pages4
ISBN (Electronic)9781538613115
ISBN (Print)9781538613122
DOIs
Publication statusPublished - Jul 2019
Externally publishedYes
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2019: Biomedical Engineering Ranging from Wellness to Intensive Care - Berlin, Germany
Duration: 23 Jul 201927 Jul 2019
Conference number: 41st
https://embc.embs.org/2019/

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2019
Abbreviated titleEMBC 2019
CountryGermany
CityBerlin
Period23/07/1927/07/19
Internet address

Cite this

Phan, D., Nguyen, N., Pathirana, P. N., Horne, M., Power, L., & Szmulewicz, D. (2019). Quantitative Assessment of Ataxic Gait using Inertial Sensing at Different Walking Speeds. In R. Barbieri (Ed.), 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 4600-4603). IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/EMBC.2019.8857189