Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area

Deepak Khanna; Srinivas Vengala; Andrew P. Miller; Navin C. Nanda; Steven G. Lloyd; Sujood Ahmed; Ashish Sinha; Farhat Mehmood; Kunal Bodiwala; Sailendra Upendram; Marappa Gownder; Harvinder S. Dod; Anthony Nunez; Albert D. Pacifico; David C. McGiffin; James K. Kirklin; Vijay K. Misra

doi:10.1111/j.0742-2822.2004.40027.x

Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area

Deepak Khanna, Srinivas Vengala, Andrew P. Miller, Navin C. Nanda, Steven G. Lloyd, Sujood Ahmed, Ashish Sinha, Farhat Mehmood, Kunal Bodiwala, Sailendra Upendram, Marappa Gownder, Harvinder S. Dod, Anthony Nunez, Albert D. Pacifico, David C. McGiffin, James K. Kirklin, Vijay K. Misra

Research output: Contribution to journal › Article › Research › peer-review

101 Citations (Scopus)

Abstract

We evaluated 44 consecutive patients who underwent standard two-dimensional (2D) and live three-dimensional (3D) transthoracic echocardiography (TTE), as well as left heart catheterization with left ventriculography. Mitral regurgitant vena contracta area (VCA) was obtained by 3D TTE by systematic and sequential cropping of the acquired 3D TTE data set. Assessment of mitral regurgitation (MR) by ventriculography was compared to measurements of VCA by 3D TTE and to 2D TTE measurements of MR jet area to left atrial area (RJA/LAA), RJA alone, vena contracta width (VCW), and calculated VCA. VCA from 3D TTE closely correlated with angiographic grading (r_s = 0.88) with very little overlap. VCA of <0.2 cm² correlated with mild MR, 0.2-0.4 cm² with moderate MR, and >0.4 cm² with severe MR by angiography. Ventriculographic grading also correlated well with 2D TTE measurements of RJA/LAA (r_s = 0.79) and RJA alone (r_s = 0.76) but with more overlap. Assessment of VCW and calculated VCA by 2D TTE agreed least with ventriculography (r_s = 0.51 and r_s = 0.55, respectively). Live 3D TTE color Doppler measurements of VCA can be used for quantitative assessment of MR and is comparable to assessment by ventriculography.

Original language	English
Pages (from-to)	737-743
Number of pages	7
Journal	Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques
Volume	21
Issue number	8
DOIs	https://doi.org/10.1111/j.0742-2822.2004.40027.x
Publication status	Published - 1 Nov 2004
Externally published	Yes

Keywords

Mitral regurgitant jet area
Mitral regurgitation
Mitral vena contracta area
Three-dimensional echocardiography

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10.1111/j.0742-2822.2004.40027.x

Cite this

Khanna, D., Vengala, S., Miller, A. P., Nanda, N. C., Lloyd, S. G., Ahmed, S., Sinha, A., Mehmood, F., Bodiwala, K., Upendram, S., Gownder, M., Dod, H. S., Nunez, A., Pacifico, A. D., McGiffin, D. C., Kirklin, J. K., & Misra, V. K. (2004). Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area. Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 21(8), 737-743. https://doi.org/10.1111/j.0742-2822.2004.40027.x

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title = "Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area",

abstract = "We evaluated 44 consecutive patients who underwent standard two-dimensional (2D) and live three-dimensional (3D) transthoracic echocardiography (TTE), as well as left heart catheterization with left ventriculography. Mitral regurgitant vena contracta area (VCA) was obtained by 3D TTE by systematic and sequential cropping of the acquired 3D TTE data set. Assessment of mitral regurgitation (MR) by ventriculography was compared to measurements of VCA by 3D TTE and to 2D TTE measurements of MR jet area to left atrial area (RJA/LAA), RJA alone, vena contracta width (VCW), and calculated VCA. VCA from 3D TTE closely correlated with angiographic grading (rs = 0.88) with very little overlap. VCA of <0.2 cm2 correlated with mild MR, 0.2-0.4 cm2 with moderate MR, and >0.4 cm2 with severe MR by angiography. Ventriculographic grading also correlated well with 2D TTE measurements of RJA/LAA (rs = 0.79) and RJA alone (rs = 0.76) but with more overlap. Assessment of VCW and calculated VCA by 2D TTE agreed least with ventriculography (rs = 0.51 and rs = 0.55, respectively). Live 3D TTE color Doppler measurements of VCA can be used for quantitative assessment of MR and is comparable to assessment by ventriculography.",

keywords = "Mitral regurgitant jet area, Mitral regurgitation, Mitral vena contracta area, Three-dimensional echocardiography",

author = "Deepak Khanna and Srinivas Vengala and Miller, {Andrew P.} and Nanda, {Navin C.} and Lloyd, {Steven G.} and Sujood Ahmed and Ashish Sinha and Farhat Mehmood and Kunal Bodiwala and Sailendra Upendram and Marappa Gownder and Dod, {Harvinder S.} and Anthony Nunez and Pacifico, {Albert D.} and McGiffin, {David C.} and Kirklin, {James K.} and Misra, {Vijay K.}",

year = "2004",

month = nov,

day = "1",

doi = "10.1111/j.0742-2822.2004.40027.x",

language = "English",

volume = "21",

pages = "737--743",

journal = "Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques",

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Khanna, D, Vengala, S, Miller, AP, Nanda, NC, Lloyd, SG, Ahmed, S, Sinha, A, Mehmood, F, Bodiwala, K, Upendram, S, Gownder, M, Dod, HS, Nunez, A, Pacifico, AD, McGiffin, DC, Kirklin, JK & Misra, VK 2004, 'Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area', Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, vol. 21, no. 8, pp. 737-743. https://doi.org/10.1111/j.0742-2822.2004.40027.x

Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area. / Khanna, Deepak; Vengala, Srinivas; Miller, Andrew P. et al.
In: Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, Vol. 21, No. 8, 01.11.2004, p. 737-743.

Research output: Contribution to journal › Article › Research › peer-review

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T1 - Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area

AU - Khanna, Deepak

AU - Vengala, Srinivas

AU - Miller, Andrew P.

AU - Nanda, Navin C.

AU - Lloyd, Steven G.

AU - Ahmed, Sujood

AU - Sinha, Ashish

AU - Mehmood, Farhat

AU - Bodiwala, Kunal

AU - Upendram, Sailendra

AU - Gownder, Marappa

AU - Dod, Harvinder S.

AU - Nunez, Anthony

AU - Pacifico, Albert D.

AU - McGiffin, David C.

AU - Kirklin, James K.

AU - Misra, Vijay K.

PY - 2004/11/1

Y1 - 2004/11/1

N2 - We evaluated 44 consecutive patients who underwent standard two-dimensional (2D) and live three-dimensional (3D) transthoracic echocardiography (TTE), as well as left heart catheterization with left ventriculography. Mitral regurgitant vena contracta area (VCA) was obtained by 3D TTE by systematic and sequential cropping of the acquired 3D TTE data set. Assessment of mitral regurgitation (MR) by ventriculography was compared to measurements of VCA by 3D TTE and to 2D TTE measurements of MR jet area to left atrial area (RJA/LAA), RJA alone, vena contracta width (VCW), and calculated VCA. VCA from 3D TTE closely correlated with angiographic grading (rs = 0.88) with very little overlap. VCA of <0.2 cm2 correlated with mild MR, 0.2-0.4 cm2 with moderate MR, and >0.4 cm2 with severe MR by angiography. Ventriculographic grading also correlated well with 2D TTE measurements of RJA/LAA (rs = 0.79) and RJA alone (rs = 0.76) but with more overlap. Assessment of VCW and calculated VCA by 2D TTE agreed least with ventriculography (rs = 0.51 and rs = 0.55, respectively). Live 3D TTE color Doppler measurements of VCA can be used for quantitative assessment of MR and is comparable to assessment by ventriculography.

AB - We evaluated 44 consecutive patients who underwent standard two-dimensional (2D) and live three-dimensional (3D) transthoracic echocardiography (TTE), as well as left heart catheterization with left ventriculography. Mitral regurgitant vena contracta area (VCA) was obtained by 3D TTE by systematic and sequential cropping of the acquired 3D TTE data set. Assessment of mitral regurgitation (MR) by ventriculography was compared to measurements of VCA by 3D TTE and to 2D TTE measurements of MR jet area to left atrial area (RJA/LAA), RJA alone, vena contracta width (VCW), and calculated VCA. VCA from 3D TTE closely correlated with angiographic grading (rs = 0.88) with very little overlap. VCA of <0.2 cm2 correlated with mild MR, 0.2-0.4 cm2 with moderate MR, and >0.4 cm2 with severe MR by angiography. Ventriculographic grading also correlated well with 2D TTE measurements of RJA/LAA (rs = 0.79) and RJA alone (rs = 0.76) but with more overlap. Assessment of VCW and calculated VCA by 2D TTE agreed least with ventriculography (rs = 0.51 and rs = 0.55, respectively). Live 3D TTE color Doppler measurements of VCA can be used for quantitative assessment of MR and is comparable to assessment by ventriculography.

KW - Mitral regurgitant jet area

KW - Mitral regurgitation

KW - Mitral vena contracta area

KW - Three-dimensional echocardiography

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U2 - 10.1111/j.0742-2822.2004.40027.x

DO - 10.1111/j.0742-2822.2004.40027.x

M3 - Article

C2 - 15546375

AN - SCOPUS:9244225672

SN - 0742-2822

VL - 21

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EP - 743

JO - Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques

JF - Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques

IS - 8

ER -

Quantification of mitral regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area

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Keywords

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