Abstract
Background: We aimed to investigate the relationship between sleep quality, mood and health-related quality of life (HRQOL) in children with CF and controls. Methods: Children (7-12. years) and adolescents (13-18. years) with CF and controls completed sleep evaluation: overnight oximetry and 14. days of actigraphy. Age-appropriate questionnaires assessed mood (Children's Depression Inventory; CDI or Beck's Depression Inventory), HRQOL (CF Questionnaire-Revised; CFQ-R or PedsQL), and sleepiness (Pediatric Daytime Sleepiness Scale). Results: 87 CF and 55 controls recruited. Children with CF had poorer sleep quality, more sleepiness and lower mood than controls, with a negative correlation between mood score and sleep efficiency. Sleepiness score was predictive of mood score and multiple CFQ-R domains. Adolescents with CF also demonstrated poorer sleep and more sleepiness than controls, but no difference in mood. Reduced sleep quality predicted lower CFQ-R scores. No correlation between sleep, mood or HRQOL in controls. Conclusions: In children and adolescents with CF, impaired sleep quality is associated with lower mood and HRQOL in an age-specific manner. Future research will aid understanding of effective strategies for prevention and treatment of mood disorders and sleep disturbance in children with CF.
| Original language | English |
|---|---|
| Pages (from-to) | 811-820 |
| Number of pages | 10 |
| Journal | Journal of Cystic Fibrosis |
| Volume | 17 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2018 |
Keywords
- Children
- Mood
- Quality of life
- Sleep
Cite this
}
Quality of life and mood in children with cystic fibrosis : Associations with sleep quality. / Vandeleur, Moya; Walter, Lisa M.; Armstrong, David S.; Robinson, Philip; Nixon, Gillian M.; Horne, Rosemary S.C.
In: Journal of Cystic Fibrosis, Vol. 17, No. 6, 11.2018, p. 811-820.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Quality of life and mood in children with cystic fibrosis
T2 - Associations with sleep quality
AU - Vandeleur, Moya
AU - Walter, Lisa M.
AU - Armstrong, David S.
AU - Robinson, Philip
AU - Nixon, Gillian M.
AU - Horne, Rosemary S.C.
PY - 2018/11
Y1 - 2018/11
N2 - Background: We aimed to investigate the relationship between sleep quality, mood and health-related quality of life (HRQOL) in children with CF and controls. Methods: Children (7-12. years) and adolescents (13-18. years) with CF and controls completed sleep evaluation: overnight oximetry and 14. days of actigraphy. Age-appropriate questionnaires assessed mood (Children's Depression Inventory; CDI or Beck's Depression Inventory), HRQOL (CF Questionnaire-Revised; CFQ-R or PedsQL), and sleepiness (Pediatric Daytime Sleepiness Scale). Results: 87 CF and 55 controls recruited. Children with CF had poorer sleep quality, more sleepiness and lower mood than controls, with a negative correlation between mood score and sleep efficiency. Sleepiness score was predictive of mood score and multiple CFQ-R domains. Adolescents with CF also demonstrated poorer sleep and more sleepiness than controls, but no difference in mood. Reduced sleep quality predicted lower CFQ-R scores. No correlation between sleep, mood or HRQOL in controls. Conclusions: In children and adolescents with CF, impaired sleep quality is associated with lower mood and HRQOL in an age-specific manner. Future research will aid understanding of effective strategies for prevention and treatment of mood disorders and sleep disturbance in children with CF.
AB - Background: We aimed to investigate the relationship between sleep quality, mood and health-related quality of life (HRQOL) in children with CF and controls. Methods: Children (7-12. years) and adolescents (13-18. years) with CF and controls completed sleep evaluation: overnight oximetry and 14. days of actigraphy. Age-appropriate questionnaires assessed mood (Children's Depression Inventory; CDI or Beck's Depression Inventory), HRQOL (CF Questionnaire-Revised; CFQ-R or PedsQL), and sleepiness (Pediatric Daytime Sleepiness Scale). Results: 87 CF and 55 controls recruited. Children with CF had poorer sleep quality, more sleepiness and lower mood than controls, with a negative correlation between mood score and sleep efficiency. Sleepiness score was predictive of mood score and multiple CFQ-R domains. Adolescents with CF also demonstrated poorer sleep and more sleepiness than controls, but no difference in mood. Reduced sleep quality predicted lower CFQ-R scores. No correlation between sleep, mood or HRQOL in controls. Conclusions: In children and adolescents with CF, impaired sleep quality is associated with lower mood and HRQOL in an age-specific manner. Future research will aid understanding of effective strategies for prevention and treatment of mood disorders and sleep disturbance in children with CF.
KW - Children
KW - Mood
KW - Quality of life
KW - Sleep
UR - http://www.scopus.com/inward/record.url?scp=85039742513&partnerID=8YFLogxK
U2 - 10.1016/j.jcf.2017.11.021
DO - 10.1016/j.jcf.2017.11.021
M3 - Article
VL - 17
SP - 811
EP - 820
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
SN - 1569-1993
IS - 6
ER -