Quality of life after intestinal resection in patients with Crohn Disease

A systematic review

Francis J. Ha, Louisa Thong, Hanan Khalil

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Background/Aims: Most patients with Crohn disease (CD) require surgery within 10 years of diagnosis. Intestinal resection is the most commonly performed operation although the effects on health-related quality of life (HRQOL), particularly long-term, are contentious. Methods: We conducted a systematic review evaluating the impact of intestinal resection on the HRQOL of CD patients, predictors of postoperative HRQOL, and patient satisfaction with surgery. Results: Nine studies including 1,108 CD patients undergoing intestinal resection were identified as eligible for inclusion. The median age at surgery was 29-41 years with varying follow-up period (range 30 days-5 years). Ileocolic resection was the most commonly performed operation on an elective basis (range 95-100%). HRQOL improved as early as 2 weeks postoperatively and lasted up to 5 years across both generic and gastrointestinal domains. Gender, smoking, and disease recurrence were potential predictors of postoperative HRQOL. Patient satisfaction is high with regard to surgery, with preference for a laparoscopic approach. Conclusion: Intestinal resection in CD patients improved HRQOL in the short- and long-term and patients describe high satisfaction about their surgery. Further studies are needed to validate potential predictors of postoperative HRQOL in this cohort.

Original languageEnglish
Pages (from-to)355-363
Number of pages9
JournalDigestive Surgery
Volume34
Issue number5
DOIs
Publication statusPublished - Aug 2017

Keywords

  • Crohn disease
  • Intestinal resection
  • Quality of life
  • Surgery

Cite this

Ha, Francis J. ; Thong, Louisa ; Khalil, Hanan. / Quality of life after intestinal resection in patients with Crohn Disease : A systematic review. In: Digestive Surgery. 2017 ; Vol. 34, No. 5. pp. 355-363.
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abstract = "Background/Aims: Most patients with Crohn disease (CD) require surgery within 10 years of diagnosis. Intestinal resection is the most commonly performed operation although the effects on health-related quality of life (HRQOL), particularly long-term, are contentious. Methods: We conducted a systematic review evaluating the impact of intestinal resection on the HRQOL of CD patients, predictors of postoperative HRQOL, and patient satisfaction with surgery. Results: Nine studies including 1,108 CD patients undergoing intestinal resection were identified as eligible for inclusion. The median age at surgery was 29-41 years with varying follow-up period (range 30 days-5 years). Ileocolic resection was the most commonly performed operation on an elective basis (range 95-100{\%}). HRQOL improved as early as 2 weeks postoperatively and lasted up to 5 years across both generic and gastrointestinal domains. Gender, smoking, and disease recurrence were potential predictors of postoperative HRQOL. Patient satisfaction is high with regard to surgery, with preference for a laparoscopic approach. Conclusion: Intestinal resection in CD patients improved HRQOL in the short- and long-term and patients describe high satisfaction about their surgery. Further studies are needed to validate potential predictors of postoperative HRQOL in this cohort.",
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Quality of life after intestinal resection in patients with Crohn Disease : A systematic review. / Ha, Francis J.; Thong, Louisa; Khalil, Hanan.

In: Digestive Surgery, Vol. 34, No. 5, 08.2017, p. 355-363.

Research output: Contribution to journalReview ArticleResearchpeer-review

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