Pyrazolo[3,4-d]pyrimidine analogues of isoguanine

Ronald J. Quinn; Peter J. Scammells

doi:10.1016/S0040-4039(00)93603-7

Pyrazolo[3,4-d]pyrimidine analogues of isoguanine

Ronald J. Quinn, Peter J. Scammells

Medicinal Chemistry

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8 Citations (Scopus)

Abstract

4-Amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one (5a) was synthesized in 68% yield in a one pot reaction involving the condensation of 5-amino-1-phenylpyrazole-4-carbonitrile with benzoyl isocyanate followed by an annulation with ammonia. © 1991.

Original language	English
Pages (from-to)	6787-6788
Number of pages	2
Journal	Tetrahedron Letters
Volume	32
Issue number	46
DOIs	https://doi.org/10.1016/S0040-4039(00)93603-7
Publication status	Published - 11 Nov 1991

Keywords

4-amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one
isocyanate
isoguanine analogue
nucleosides
ring annulation

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abstract = "4-Amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one (5a) was synthesized in 68% yield in a one pot reaction involving the condensation of 5-amino-1-phenylpyrazole-4-carbonitrile with benzoyl isocyanate followed by an annulation with ammonia. {\textcopyright} 1991.",

keywords = "4-amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one, isocyanate, isoguanine analogue, nucleosides, ring annulation",

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T1 - Pyrazolo[3,4-d]pyrimidine analogues of isoguanine

AU - Quinn, Ronald J.

AU - Scammells, Peter J.

PY - 1991/11/11

Y1 - 1991/11/11

N2 - 4-Amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one (5a) was synthesized in 68% yield in a one pot reaction involving the condensation of 5-amino-1-phenylpyrazole-4-carbonitrile with benzoyl isocyanate followed by an annulation with ammonia. © 1991.

AB - 4-Amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one (5a) was synthesized in 68% yield in a one pot reaction involving the condensation of 5-amino-1-phenylpyrazole-4-carbonitrile with benzoyl isocyanate followed by an annulation with ammonia. © 1991.

KW - 4-amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one

KW - isocyanate

KW - isoguanine analogue

KW - nucleosides

KW - ring annulation

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DO - 10.1016/S0040-4039(00)93603-7

M3 - Article

AN - SCOPUS:0026047354

VL - 32

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EP - 6788

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 46

ER -

Pyrazolo[3,4-d]pyrimidine analogues of isoguanine

Abstract

Keywords

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