Pyrazolo[1,5-α][1,3,5]triazines (5-Aza-9-deazapurines): Synthesis and biological activity

Anton V. Dolzhenko, Anna V. Dolzhenko, Wai Keung Chui

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Abstract

The present review gives an account on the synthetic routes to pyrazolo[1,5-α][1,3,5]triazine system, which is an isostere of purine, and polyfused systems bearing this heterocyclic core. Data concerning biological activity of compounds with pyrazolo[1,5-α][1,3,5]triazine skeleton are also discussed.

Original languageEnglish
Pages (from-to)1575-1622
Number of pages48
JournalHeterocycles
Volume75
Issue number7
DOIs
Publication statusPublished - 1 Jul 2008
Externally publishedYes

Keywords

  • Fused Pyrazole
  • Fused s-Triazine
  • Purine Isostere
  • Pyrazolo[1,5,α]triazine
  • Ring Closure

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