Abstract
Purpose:.To determine if time of Pulse Wave Velocity (PWV) determination can be a reliable tool to detect risk to develop cardiovascular disease (CVD).
Method: PWV was determined by a non invasive method using the left external carotid artery as the central point and left dorsalis pedis artery as the peripheral point. Pulses were recorded from electronic sensors simultaneously with a single lead ECG and time delay between the two pulses computed. Shorter time indicates decreased arterial wall elasticity. Family history (FH) taken; waist circumference (WC) and BP measured.
Materials: Total of 339 clinically asymptomatic Filipino subjects in a rural area were examined. Of these 176 w/ FH of CVD; 58 w/ abnormal WC; 58 w/ borderline hypertension; and, 8 w/ definite hypertension. 98 subjects without these negative parameters were considered normal.
Results: PWV time in normal subjecs - 0.151 sec. In abnormal subjects PWV time in sec. - 1) w/ + FH of CVD - 0.140; 2) w/ abnormal WC - Males - 0.132, Females - 0.127; 3) w/ borderline hypertension - 0.122; and 4) definite hypertensives - 0.105 - all significant statistically below the normal
Discussion: Positive FH of CVD, increased WC and hypertension are accepted high risk factors to develop CVD. In our study, we showed that subjects with these aggravating parameters showed significantly lower PWV time compared to normals. It follows, therefore, that individuals with low PWV time can be considered to have high risk to develop CVD, It can therefore be a useful screening tool for CVD
Conclusion: PWV time determination can be a useful tool to detect individuals who have high risk to develop CVD.
Method: PWV was determined by a non invasive method using the left external carotid artery as the central point and left dorsalis pedis artery as the peripheral point. Pulses were recorded from electronic sensors simultaneously with a single lead ECG and time delay between the two pulses computed. Shorter time indicates decreased arterial wall elasticity. Family history (FH) taken; waist circumference (WC) and BP measured.
Materials: Total of 339 clinically asymptomatic Filipino subjects in a rural area were examined. Of these 176 w/ FH of CVD; 58 w/ abnormal WC; 58 w/ borderline hypertension; and, 8 w/ definite hypertension. 98 subjects without these negative parameters were considered normal.
Results: PWV time in normal subjecs - 0.151 sec. In abnormal subjects PWV time in sec. - 1) w/ + FH of CVD - 0.140; 2) w/ abnormal WC - Males - 0.132, Females - 0.127; 3) w/ borderline hypertension - 0.122; and 4) definite hypertensives - 0.105 - all significant statistically below the normal
Discussion: Positive FH of CVD, increased WC and hypertension are accepted high risk factors to develop CVD. In our study, we showed that subjects with these aggravating parameters showed significantly lower PWV time compared to normals. It follows, therefore, that individuals with low PWV time can be considered to have high risk to develop CVD, It can therefore be a useful screening tool for CVD
Conclusion: PWV time determination can be a useful tool to detect individuals who have high risk to develop CVD.
| Original language | English |
|---|---|
| Pages | e633 |
| Number of pages | 1 |
| DOIs | |
| Publication status | Published - 2009 |
| Externally published | Yes |
| Event | International Symposium on Atherosclerosis 2009 - Boston, United States of America Duration: 14 Jun 2009 → 18 Jun 2009 Conference number: 15th https://www.sciencedirect.com/journal/atherosclerosis-supplements/vol/10/issue/2 |
Conference
| Conference | International Symposium on Atherosclerosis 2009 |
|---|---|
| Country/Territory | United States of America |
| City | Boston |
| Period | 14/06/09 → 18/06/09 |
| Internet address |
Keywords
- Cardiovascular disease
- Pulse Wave Velocity
