Psychometric evaluation supported construct validity, temporal stability, and responsiveness of the Osteoarthritis Questionnaire

Ljoudmila Busija, Richard H. Osborne, Gemma Tatangelo, Silvana Niutta, Rachelle Buchbinder

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Objectives: The Osteoarthritis Questionnaire (OA-Quest) is a new measure of individual burden of osteoarthritis, composing seven brief (4–11 items; total 42 items), independent scales. This study describes the psychometric evaluation of the OA-Quest. Specifically, temporal stability, convergent and discriminant validity, and responsiveness of the OA-Quest to joint replacement surgery were examined. Study Design and Setting: Participants were drawn from rheumatology (n = 62), orthopedic (n = 90), and community (n = 175) settings. Temporal stability of the OA-Quest was evaluated over a 2-week period and was assessed with intraclass correlation coefficients. Responsiveness was assessed with standardized effect sizes and paired samples t-tests. Convergent and discriminant validity was assessed with a multitrait multimethod confirmatory factor analysis (MTMM CFA). Results: The OA-Quest scales had high temporal stability, with intraclass correlation coefficients between 0.75 (lost productivity) and 0.94 (physical limitations) and showed improvements of expected magnitude and direction 3 months after joint replacement surgery, supporting their responsiveness. MTMM CFA supported the convergent and discriminant validity of the OA-Quest, demonstrated by adequate model fit (χ2 = 483.54, df = 184, P < 0.001, comparative fit index = 0.95, Tucker-Lewis index = 0.93, root mean square error of approximation = 0.07, standardized root mean square residual = 0.06) and factor loadings of the expected magnitude and direction. Conclusion: The OA-Quest has strong evidence of temporal stability, construct validity, and is responsive to change following joint replacement surgery.

Original languageEnglish
Pages (from-to)11-21
Number of pages11
JournalJournal of Clinical Epidemiology
Publication statusPublished - Oct 2019


  • Measurement
  • Osteoarthritis
  • Patient-reported outcomes

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