Pseudomonas aeruginosa bacteremia over a 10-year period: multidrug resistance and outcomes in transplant recipients

L E Johnson, E MC D'Agata, David L Paterson, L Clarke, Z A Qureshi, B A Potoski, Anton Yariv Peleg

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64 Citations (Scopus)

Abstract

AIM: Transplant recipients are at risk for hospital-acquired infections (HAIs), including those caused by Pseudomonas aeruginosa. Of all HAIs, bloodstream infection (BSI) remains one of the most life-threatening. METHODS: Over a 10-year period, we studied 503 patients, including 149 transplant recipients, with pseudomonal BSI from the University of Pittsburgh Medical Center. Trends in antimicrobial susceptibility, risk factors for multidrug resistance (MDR), and outcomes were compared between transplant and non-transplant patients. RESULTS: Resistance to all antibiotic classes was significantly greater in pseudomonal blood culture isolates from transplant compared with non-transplant patients (P
Original languageEnglish
Pages (from-to)227 - 234
Number of pages8
JournalTransplant Infectious Disease
Volume11
Issue number3
DOIs
Publication statusPublished - 2009
Externally publishedYes

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