Abstract
The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a wellunderstood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.
| Original language | English |
|---|---|
| Title of host publication | Drosophila: Methods and Protocols |
| Editors | Christian Dahmann |
| Place of Publication | New York NY USA |
| Publisher | Humana Press |
| Pages | 291-302 |
| Number of pages | 12 |
| Edition | 2 |
| ISBN (Electronic) | 9781493963713 |
| ISBN (Print) | 978149396369 |
| DOIs | |
| Publication status | Published - 12 Oct 2016 |
Publication series
| Name | Methods in Molecular Biology |
|---|---|
| Publisher | Humana Press |
| Volume | 1478 |
| ISSN (Print) | 1064-3745 |
| ISSN (Electronic) | 1940-6029 |
Keywords
- Aging
- Backcross
- Diet
- Drosophila melanogaster
- Genetic interventions
- Life span
- Method
- Pharmacological interventions
Cite this
Piper, M. D. W., & Partridge, L. (2016). Protocols to study aging in Drosophila. In C. Dahmann (Ed.), Drosophila: Methods and Protocols (2 ed., pp. 291-302). (Methods in Molecular Biology; Vol. 1478). New York NY USA: Humana Press. https://doi.org/10.1007/978-1-4939-6371-3_18