Protocols to study aging in Drosophila

Matthew D W Piper, Linda Partridge

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

27 Citations (Scopus)


The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a wellunderstood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.
Original languageEnglish
Title of host publicationDrosophila: Methods and Protocols
EditorsChristian Dahmann
Place of PublicationNew York NY USA
PublisherHumana Press
Number of pages12
ISBN (Electronic)9781493963713
ISBN (Print)978149396369
Publication statusPublished - 12 Oct 2016

Publication series

NameMethods in Molecular Biology
PublisherHumana Press
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029


  • Aging
  • Backcross
  • Diet
  • Drosophila melanogaster
  • Genetic interventions
  • Life span
  • Method
  • Pharmacological interventions

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