Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation

H Tran; M Collecutt; S Whitehead; Hatem Hassan Salem

doi:10.1111/j.1445-5994.2010.02237.x

Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation

H Tran, M Collecutt, S Whitehead, Hatem Hassan Salem

Australian Centre for Blood Diseases

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Abstract

Background: Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anticoagulation. Aim: To evaluate the efficacy and safety of Prothrombinex-VF used alone in warfarin reversal. Methods: Adult patients requiring urgent reversal of warfarin anticoagulation were defined as having achieved complete (target international normalized ratio (INR)

Original language	English
Pages (from-to)	337 - 343
Number of pages	7
Journal	Internal Medicine Journal
Volume	41
Issue number	4
DOIs	https://doi.org/10.1111/j.1445-5994.2010.02237.x
Publication status	Published - 2011

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10.1111/j.1445-5994.2010.02237.x

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abstract = "Background: Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anticoagulation. Aim: To evaluate the efficacy and safety of Prothrombinex-VF used alone in warfarin reversal. Methods: Adult patients requiring urgent reversal of warfarin anticoagulation were defined as having achieved complete (target international normalized ratio (INR)",

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AB - Background: Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anticoagulation. Aim: To evaluate the efficacy and safety of Prothrombinex-VF used alone in warfarin reversal. Methods: Adult patients requiring urgent reversal of warfarin anticoagulation were defined as having achieved complete (target international normalized ratio (INR)

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JO - Internal Medicine Journal

JF - Internal Medicine Journal

SN - 1444-0903

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ER -

Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation

Abstract

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