Proteomics and the search for biomarkers of female reproductive diseases

Katie L. Meehan, Adam Rainczuk, Lois A. Salamonsen, Andrew N. Stephens

Research output: Contribution to journalArticleOtherpeer-review

20 Citations (Scopus)

Abstract

Over the past decade, high-throughput proteomics technologies have evolved considerably and have become increasingly more commonly applied to the investigation of female reproductive diseases. Proteomic approaches facilitate the identification of new disease biomarkers by comparing the abundance of hundreds of proteins simultaneously to find those specific to a particular clinical condition. Some of the best studied areas of female reproductive biology applying proteomics include gynaecological cancers, endometriosis and endometrial infertility. This review will discuss the progress that has been made in these areas and will highlight some of the emerging technologies that promise to contribute to better understanding of the female reproductive disease.

Original languageEnglish
Pages (from-to)505-519
Number of pages15
JournalReproduction
Volume140
Issue number4
DOIs
Publication statusPublished - Oct 2010
Externally publishedYes

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