Prostate Biopsy-related Infection: A Systematic Review of Risk Factors, Prevention Strategies, and Management Approaches

Matthew J. Roberts, Harrison Y. Bennett, Patrick N. Harris, Michael Holmes, Jeremy Grummet, Kurt G Naber, Florian M E Wagenlehner

Research output: Contribution to journalReview ArticleResearchpeer-review

85 Citations (Scopus)


A systematic review to identify risk factors for prostate biopsy-related infection, preventative strategies, and optimal management of infectious complications was conducted. Significant risk factors for postbiopsy infection include urogenital infection, antibiotic use, international travel, hospital exposure, bacteriuria, previous transrectal biopsy, and resistance of fecal flora to antibiotic prophylaxis (especially fluoroquinolones). Patients at risk may benefit from an adjusted biopsy protocol comprising transrectal biopsy under targeted prophylaxis, and/or the use of rectal disinfection techniques or using a transperineal approach. Management of biopsy-related infection should be based on individual risk and local resistance profiles with input from multiple specialties.

Original languageEnglish
Pages (from-to)11-21
Number of pages11
Publication statusPublished - 1 Jun 2017

Cite this