Prospective evaluation of respiratory exacerbations in children with cystic fibrosis from newborn screening to 5 years of age

Catherine A Byrnes, Suzanna Vidmar, Joyce L Cheney, John B Carlin, David Stuart Armstrong, Peter J Cooper, Keith Grimwood, Marjory L Moodie, Colin F Robertson, Margaret Rosenfeld, Harm A Tiddens, Claire Wainwright

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55 Citations (Scopus)

Abstract

Newborn screening allows novel treatments for cystic fibrosis (CF) to be trialled in early childhood before irreversible lung injury occurs. As respiratory exacerbations are a potential trial outcome variable, we determined their rate, duration and clinical features in preschool children with CF; and whether they were associted with growth, lung structure and function at age 5 years.
Original languageEnglish
Pages (from-to)643 - 651
Number of pages9
JournalThorax
Volume68
Issue number7
DOIs
Publication statusPublished - 2013
Externally publishedYes

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