TY - JOUR
T1 - Prone positioning in acute respiratory distress syndrome after abdominal surgery
T2 - a multicenter retrospective study: SAPRONADONF (Study of Ards and PRONe position After abDOmiNal surgery in France)
AU - Gaudry, Stéphane
AU - Tuffet, Samuel
AU - Lukaszewicz, Anne-Claire
AU - Laplace, Christian
AU - Zucman, Noémie
AU - Pocard, Marc
AU - Costaglioli, Bruno
AU - Msika, Simon
AU - Duranteau, Jacques
AU - Payen, Didier
AU - Dreyfuss, Didier
AU - Hajage, David
AU - Ricard, Jean-Damien
PY - 2017/2/24
Y1 - 2017/2/24
N2 - Background: The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS. Uncertainties remain as to whether or not ARDS patients in the postoperative period of abdominal surgery should be turned prone because of the risk of abdominal complications. Our aim was to investigate the prevalence of surgical complications between patients with and without prone position after abdominal surgery. Methods: This study was a multicenter retrospective cohort of patients with ARDS in a context of recent abdominal surgery. Primary outcome was the number of patients who had at least one surgical complication that could be induced or worsened by prone position. Secondary outcomes included effects of prone position on oxygenation. Data from the prone group were compared with those from the supine group (not having undergone at least a prone position session). Results: Among 98 patients included, 36 (37%) had at least one prone position session. The rate of surgical complications induced or worsened by prone position did not differ between prone and supine groups [respectively, 14 (39%) vs 27 (44%); p = 0.65]. After propensity score application, there was no significant difference between the two groups (OR 0.72 [0.26–2.02], p = 0.54). Revision surgery did not differ between the groups. The first prone session significantly increased PaO2/FiO2 ratio from 95 ± 47 to 189 ± 92 mmHg, p < 0.0001. Conclusion: Prone position of ARDS patients after abdominal surgery was not associated with an increased rate of surgical complication. Intensivists should not refrain from proning these patients.
AB - Background: The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS. Uncertainties remain as to whether or not ARDS patients in the postoperative period of abdominal surgery should be turned prone because of the risk of abdominal complications. Our aim was to investigate the prevalence of surgical complications between patients with and without prone position after abdominal surgery. Methods: This study was a multicenter retrospective cohort of patients with ARDS in a context of recent abdominal surgery. Primary outcome was the number of patients who had at least one surgical complication that could be induced or worsened by prone position. Secondary outcomes included effects of prone position on oxygenation. Data from the prone group were compared with those from the supine group (not having undergone at least a prone position session). Results: Among 98 patients included, 36 (37%) had at least one prone position session. The rate of surgical complications induced or worsened by prone position did not differ between prone and supine groups [respectively, 14 (39%) vs 27 (44%); p = 0.65]. After propensity score application, there was no significant difference between the two groups (OR 0.72 [0.26–2.02], p = 0.54). Revision surgery did not differ between the groups. The first prone session significantly increased PaO2/FiO2 ratio from 95 ± 47 to 189 ± 92 mmHg, p < 0.0001. Conclusion: Prone position of ARDS patients after abdominal surgery was not associated with an increased rate of surgical complication. Intensivists should not refrain from proning these patients.
KW - ARDS
KW - Mechanical ventilation
KW - Prone position
UR - http://www.scopus.com/inward/record.url?scp=85013961827&partnerID=8YFLogxK
U2 - 10.1186/s13613-017-0235-z
DO - 10.1186/s13613-017-0235-z
M3 - Article
AN - SCOPUS:85013961827
SN - 2110-5820
VL - 7
JO - Annals of Intensive Care
JF - Annals of Intensive Care
M1 - 21
ER -