Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: Reversibility of the early metabolite abnormalities relates with a good outcome

Maria De Fátima Viana Vasco Aragão, Meng Law, João Prola Netto, Marcelo Moraes Valença, Thomas Naidich

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)


In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (1H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) 1H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early 1H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.

Original languageEnglish
Pages (from-to)55-57
Number of pages3
JournalArquivos de Neuro-Psiquiatria
Issue number1
Publication statusPublished - 1 Mar 2009
Externally publishedYes


  • Hypoxia
  • Magnetic resonance spectroscopy
  • Near drowning

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