TY - JOUR
T1 - Profiles of Executive Function Across Children with Distinct Brain Disorders
T2 - Traumatic Brain Injury, Stroke, and Brain Tumor
AU - Araujo, Gabriel C.
AU - Antonini, Tanya N.
AU - Anderson, Vicki
AU - Vannatta, Kathryn A.
AU - Salley, Christina G.
AU - Bigler, Erin D
AU - Taylor, H. Gerry
AU - Gerhardt, Cynthia
AU - Rubin, Kenneth
AU - Dennis, Maureen
AU - Bruckard, Warren
AU - Mackay, Mark T
AU - Gordon, Anne L
AU - Hajek Koterba, Christine
AU - Gomes, Alison
AU - Greenham, Mardee
AU - Owen Yeates, Keith
PY - 2017/8/1
Y1 - 2017/8/1
N2 - Objectives: This study examined whether children with distinct brain disorders show different profiles of strengths and weaknesses in executive functions, and differ from children without brain disorder. Methods: Participants were children with traumatic brain injury (N=82; 8-13 years of age), arterial ischemic stroke (N=36; 6-16 years of age), and brain tumor (N=74; 9-18 years of age), each with a corresponding matched comparison group consisting of children with orthopedic injury (N=61), asthma (N=15), and classmates without medical illness (N=68), respectively. Shifting, inhibition, and working memory were assessed, respectively, using three Test of Everyday Attention: Children's Version (TEA-Ch) subtests: Creature Counting, Walk-Don't-Walk, and Code Transmission. Comparison groups did not differ in TEA-Ch performance and were merged into a single control group. Profile analysis was used to examine group differences in TEA-Ch subtest scaled scores after controlling for maternal education and age. Results: As a whole, children with brain disorder performed more poorly than controls on measures of executive function. Relative to controls, the three brain injury groups showed significantly different profiles of executive functions. Importantly, post hoc tests revealed that performance on TEA-Ch subtests differed among the brain disorder groups. Conclusions: Results suggest that different childhood brain disorders result in distinct patterns of executive function deficits that differ from children without brain disorder. Implications for clinical practice and future research are discussed.
AB - Objectives: This study examined whether children with distinct brain disorders show different profiles of strengths and weaknesses in executive functions, and differ from children without brain disorder. Methods: Participants were children with traumatic brain injury (N=82; 8-13 years of age), arterial ischemic stroke (N=36; 6-16 years of age), and brain tumor (N=74; 9-18 years of age), each with a corresponding matched comparison group consisting of children with orthopedic injury (N=61), asthma (N=15), and classmates without medical illness (N=68), respectively. Shifting, inhibition, and working memory were assessed, respectively, using three Test of Everyday Attention: Children's Version (TEA-Ch) subtests: Creature Counting, Walk-Don't-Walk, and Code Transmission. Comparison groups did not differ in TEA-Ch performance and were merged into a single control group. Profile analysis was used to examine group differences in TEA-Ch subtest scaled scores after controlling for maternal education and age. Results: As a whole, children with brain disorder performed more poorly than controls on measures of executive function. Relative to controls, the three brain injury groups showed significantly different profiles of executive functions. Importantly, post hoc tests revealed that performance on TEA-Ch subtests differed among the brain disorder groups. Conclusions: Results suggest that different childhood brain disorders result in distinct patterns of executive function deficits that differ from children without brain disorder. Implications for clinical practice and future research are discussed.
KW - Executive functions
KW - Inhibition
KW - Pediatric brain disorders
KW - Shifting
KW - TEA-Ch
KW - Working memory
UR - http://www.scopus.com/inward/record.url?scp=85019250189&partnerID=8YFLogxK
U2 - 10.1017/S1355617717000364
DO - 10.1017/S1355617717000364
M3 - Article
AN - SCOPUS:85019250189
VL - 23
SP - 529
EP - 538
JO - Journal of the International Neuropsychological Society
JF - Journal of the International Neuropsychological Society
SN - 1355-6177
IS - 7
ER -