Production and characterization of monoclonal antibodies against formalin-inactivated Nipah virus isolated from the lungs of a pig

Tadao Imada, Mohd Ali Abdul Rahman, Yoshihito Kashiwazaki, Nobuhiko Tanimura, Sharifah Syed Hassan, Aziz Jamaluddin

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11 Citations (Scopus)

Abstract

Eight clones of monoclonal antibodies (Mabs) to Nipah virus (NV) were produced against formalin-inactivated NV antigens. They reacted positive by indirect immunofluorescent antibody test, and one of them also demonstrated virus neutralizing activity. They were classified into six different types based on their biological properties. These Mabs will be useful for immunodiagnosis of NV infections in animals and further research studies involving the genomes and proteins of NV.

Original languageEnglish
Pages (from-to)81-83
Number of pages3
JournalJournal of Veterinary Medical Science
Volume66
Issue number1
DOIs
Publication statusPublished - Jan 2004
Externally publishedYes

Keywords

  • Monoclonal antibody
  • Nipah virus

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