Probiotic yogurt improves body mass index and fasting insulin levels without affecting serum leptin and adiponectin levels in non-alcoholic fatty liver disease (NAFLD)

Safoora Nabavi, Maryam Rafraf, Mohammad hossein Somi, Aziz Homayouni-Rad, Mohammad Asghari-Jafarabadi

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Abstract

There is evidence of possible beneficial effects of probiotic products in non-alcoholic fatty liver disease (NAFLD). Here the effects of probiotic yogurt consumption on obesity values, fasting insulin, insulin resistance, and serum leptin and adiponectin levels in NAFLD patients were investigated by a randomized double-blind controlled clinical trial. Seventy-two subjects, aged between 23 and 63 years, were divided into two groups. Subjects consumed either 300g/day of probiotic yogurt or 300g/day of conventional yogurt for 8weeks. Probiotic yogurt consumption resulted in a significant reduction in weight, body mass index, and serum levels of fasting insulin as compared with that in the control group. No significant changes were observed in waist circumference, homeostasis model assessment insulin resistance, serum leptin, adiponectin, and leptin to adiponectin ratio in both groups. Our study suggests that probiotic yogurt consumption improved body mass index and insulin levels and may be applicable in reducing risk factors of NAFLD.

Original languageEnglish
Article number1279
Pages (from-to)684-691
Number of pages8
JournalJournal of Functional Foods
Volume18
DOIs
Publication statusPublished - 1 Oct 2015
Externally publishedYes

Keywords

  • Adiponectin
  • Insulin
  • Leptin
  • Non-alcoholic fatty liver disease
  • Obesity values
  • Probiotic yogurt

Cite this