Primary liver cell carcinoma complicating autoimmune chronic active hepatitis

A. W. Jakobovits, P. R. Gibson, F. J. Dudley

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)


In a group of 50 patients seen with primary liver cell carcinoma over a period of five years, 38 had cirrhosis. In four patients the cirrhosis was due to autoimmune chronic active hepatitis. None of the patients had markers of hepatitis B virus infection, but in three of the four, serum autoantibodies were present. Coexisting autoimmune disease was present in two. Corticosteroids induced remission in all patients, and the liver disease appeared quiescent at the time primary liver cell carcinoma developed.

Original languageEnglish
Pages (from-to)694-699
Number of pages6
JournalDigestive Diseases and Sciences
Issue number8
Publication statusPublished - 1 Aug 1981
Externally publishedYes

Cite this