Surgical site infection is common (5-20 ) and may be associated with significant morbidity and even mortality. Crucial immune mechanisms such as neutrophil phagocytosis of bacteria may be impaired during the perioperative period. Multiple randomized controlled trials and systematic reviews have consistently shown antibiotic prophylaxis to be effective in preventing infections after many types of surgery. For effective prophylaxis, appropriate antibiotics should be given before skin incision as recommended by the recent WHO Safe Surgery Saves Lives surgical safety checklist. Potentially modifiable perioperative factors under control of the anaesthetist can influence the incidence of surgical site infection.
|Pages (from-to)||151 - 156|
|Number of pages||6|
|Journal||Continuing Education in Anaesthesia, Critical Care and Pain|
|Publication status||Published - 2011|